2,2'-Dipyridyldisulfide
Names | |
---|---|
Preferred IUPAC name 2,2′-Disulfanediyldipyridine | |
Other names 1,2-Di(pyridin-2-yl)disulfane (not recommended) 2,2′-Dipyridyldisulfide 2,2′-Dipyridyldisulphide Aldrithiol-2 | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
ChEBI |
|
ChEMBL |
|
ChemSpider |
|
ECHA InfoCard | 100.016.676 |
EC Number |
|
PubChem CID |
|
UNII |
|
CompTox Dashboard (EPA) |
|
InChI
| |
| |
Properties | |
Chemical formula | C10H8N2S2 |
Molar mass | 220.31 g·mol−1 |
Melting point | 56 to 58 °C (133 to 136 °F; 329 to 331 K) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards | Irritant (Xi) |
GHS labelling: | |
Pictograms | |
Warning | |
Hazard statements | H315, H319, H335 |
Precautionary statements | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references |
Chemical compound
2,2′-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols[1][2] and activating carboxylic acid for coupling reactions, as in the following reaction:[3]
Uses
It is also used in molecular biology as an oxidising agent, for example to oxidise free thiols to form disulfide bonds in proteins.
References
- ^ Futaki S. and Kitagawa K. (1994). "Peptide-Unit Assembling Using Disulfide Cross-Linking - a New Approach for Construction of Protein Models". Tetrahedron Lett. 35 (8): 1267–1270. doi:10.1016/0040-4039(94)88040-9.
- ^ "Special Reagents for Thiol Groups". Aldrichimica Acta. 4 (3): 33–46.
- ^ Thalmann A., Oertle K. and Gerlach H (1985). "Ricinelaidic acid lactone". Org. Synth. 7: 470. doi:10.15227/orgsyn.063.0192.
- v
- t
- e