AK3

AK3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZD8
Identifiers
Aliases	AK3, AK3L1, AK6, AKL3L, AKL3L1, FIX, adenylate kinase 3
External IDs	OMIM: 609290; MGI: 1860835; HomoloGene: 21744; GeneCards: AK3; OMA:AK3 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p24.1 Start 4,709,556 bp[1] End 4,742,043 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C1 Start 28,998,233 bp[2] End 29,025,361 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cardiac muscle tissue of right atrium myocardium of left ventricle skin of arm deltoid muscle tibialis anterior muscle mucosa of ileum jejunal mucosa vastus lateralis muscle biceps brachii right ventricle Top expressed in epithelium of stomach parotid gland pyloric antrum submandibular gland seminal vesicula left colon brown adipose tissue right kidney retinal pigment epithelium mucous cell of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity nucleotide binding nucleobase-containing compound kinase activity GTP binding ATP binding protein binding phosphotransferase activity, phosphate group as acceptor kinase activity nucleoside triphosphate adenylate kinase activity adenylate kinase activity Cellular component mitochondrial matrix mitochondrion Biological process UTP metabolic process blood coagulation nucleobase-containing compound metabolic process phosphorylation AMP metabolic process GTP metabolic process ITP metabolic process nucleoside monophosphate phosphorylation ADP biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50808 56248 Ensembl ENSG00000147853 ENSMUSG00000024782 UniProt Q9UIJ7 Q9WTP7 RefSeq (mRNA) NM_016282 NM_001199852 NM_001199853 NM_001199854 NM_001199855 NM_001199856 NM_021299 NM_001365071 RefSeq (protein) NP_001186781 NP_001186782 NP_001186784 NP_001186785 NP_057366 NP_067274 NP_001352000 Location (UCSC) Chr 9: 4.71 – 4.74 Mb Chr 19: 29 – 29.03 Mb PubMed search [3] [4]
Wikidata
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Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene. ^[5]

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.

• PDBe-KB provides an overview of all the structure information available in the PDB for Human GTP:AMP phosphotransferase AK3, mitochondrial (AK3)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.