ARHGEF3 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | ARHGEF3, GEF3, STA3, XPLN, Rho guanine nucleotide exchange factor 3 |
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External IDs | OMIM: 612115; MGI: 1918954; HomoloGene: 41329; GeneCards: ARHGEF3; OMA:ARHGEF3 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3p14.3 | Start | 56,727,418 bp[1] |
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End | 57,079,329 bp[1] |
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Gene location (Mouse) |
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![Chromosome 14 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Ideogram_house_mouse_chromosome_14.svg/260px-Ideogram_house_mouse_chromosome_14.svg.png) | Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14 A3|14 16.09 cM | Start | 26,836,856 bp[2] |
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End | 27,125,868 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - glomerulus
- metanephric glomerulus
- endothelial cell
- Epithelium of choroid plexus
- Brodmann area 23
- germinal epithelium
- middle temporal gyrus
- granulocyte
- oral cavity
- parietal pleura
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| Top expressed in | - granulocyte
- lobe of cerebellum
- pontine nuclei
- cerebellar vermis
- right lung
- right lung lobe
- subiculum
- deep cerebellar nuclei
- olfactory tubercle
- lateral septal nucleus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/f/f8/PBB_GE_ARHGEF3_218501_at_fs.png/250px-PBB_GE_ARHGEF3_218501_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- guanyl-nucleotide exchange factor activity
| Cellular component | - cytoplasm
- cytosol
- intracellular anatomical structure
| Biological process | - regulation of Rho protein signal transduction
- intracellular signal transduction
- regulation of small GTPase mediated signal transduction
- Rho protein signal transduction
- positive regulation of apoptotic process
- G protein-coupled receptor signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001128615 NM_001128616 NM_001289698 NM_019555 NM_001377407
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NM_001377408 NM_001377409 NM_001377410 NM_001377411 NM_001377412 NM_001377413 NM_001377414 NM_001377415 |
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NM_001289686 NM_001289687 NM_001289688 NM_027871 |
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RefSeq (protein) | NP_001122087 NP_001122088 NP_001276627 NP_062455 NP_001364336
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NP_001364337 NP_001364338 NP_001364339 NP_001364340 NP_001364341 NP_001364342 NP_001364343 NP_001364344 |
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NP_001276615 NP_001276616 NP_001276617 NP_082147 |
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Location (UCSC) | Chr 3: 56.73 – 57.08 Mb | Chr 14: 26.84 – 27.13 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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