Acetylenedicarboxylate decarboxylase

Class of enzymes
Acetylenedicarboxylate decarboxylase
Identifiers
EC no.4.1.1.78
CAS no.72561-10-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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The enzyme acetylenedicarboxylate decarboxylase (EC 4.1.1.78) catalyzes the chemical reaction

acetylenedicarboxylate + H2O {\displaystyle \rightleftharpoons } pyruvate + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.

References

  • Yamada EW, Jakoby WB (September 1958). "Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate". The Journal of Biological Chemistry. 233 (3): 706–11. PMID 13575441.
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Carbon–carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases4.1.2: Aldehyde-lyases4.1.3: Oxo-acid-lyases4.1.99: Other
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