ADAP2 |
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Identifiers |
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Aliases | ADAP2, CENTA2, HSA272195, cent-b, ArfGAP with dual PH domains 2 |
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External IDs | OMIM: 608635; MGI: 2663075; HomoloGene: 10179; GeneCards: ADAP2; OMA:ADAP2 - orthologs |
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Gene location (Human) |
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![Chromosome 17 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/Ideogram_human_chromosome_17.svg/300px-Ideogram_human_chromosome_17.svg.png) | Chr. | Chromosome 17 (human)[1] |
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| Band | 17q11.2 | Start | 30,906,344 bp[1] |
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End | 30,959,322 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11 B5|11 47.56 cM | Start | 80,154,105 bp[2] |
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End | 80,178,958 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - monocyte
- synovial membrane
- amniotic fluid
- granulocyte
- placenta
- spleen
- trabecular bone
- gingival epithelium
- blood
- synovial joint
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| Top expressed in | - Rostral migratory stream
- right kidney
- stroma of bone marrow
- lumbar subsegment of spinal cord
- left lobe of liver
- human kidney
- jejunum
- blastocyst
- duodenum
- proximal tubule
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/6/6a/PBB_GE_CENTA2_219358_s_at_fs.png/250px-PBB_GE_CENTA2_219358_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - inositol 1,3,4,5 tetrakisphosphate binding
- protein-macromolecule adaptor activity
- phosphatidylinositol-4,5-bisphosphate binding
- protein binding
- phosphatidylinositol-3,4,5-trisphosphate binding
- metal ion binding
- GTPase activator activity
- phosphatidylinositol-3,4-bisphosphate binding
- phosphatidylinositol bisphosphate binding
| Cellular component | - cytoplasm
- plasma membrane
- mitochondrial envelope
- membrane
| Biological process | - heart development
- positive regulation of GTPase activity
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001346712 NM_001346714 NM_001346716 NM_018404 |
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RefSeq (protein) | |
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NP_001333641 NP_001333643 NP_001333645 NP_060874 |
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Location (UCSC) | Chr 17: 30.91 – 30.96 Mb | Chr 11: 80.15 – 80.18 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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