CHD5 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/8/86/Protein_CHD5_PDB_1mm2.png/250px-Protein_CHD5_PDB_1mm2.png) |
Identifiers |
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Aliases | CHD5, CHD-5, chromodomain helicase DNA binding protein 5, PMNDS |
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External IDs | OMIM: 610771; MGI: 3036258; HomoloGene: 56712; GeneCards: CHD5; OMA:CHD5 - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1p36.31 | Start | 6,101,787 bp[1] |
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End | 6,180,321 bp[1] |
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Gene location (Mouse) |
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![Chromosome 4 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Ideogram_house_mouse_chromosome_4.svg/260px-Ideogram_house_mouse_chromosome_4.svg.png) | Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4|4 E2 | Start | 152,423,108 bp[2] |
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End | 152,474,651 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sperm
- right frontal lobe
- cingulate gyrus
- anterior cingulate cortex
- Brodmann area 10
- Brodmann area 9
- pituitary gland
- left testis
- right testis
- primary visual cortex
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| Top expressed in | - subiculum
- central gray substance of midbrain
- dorsal tegmental nucleus
- cingulate gyrus
- visual cortex
- habenula
- lateral hypothalamus
- primary visual cortex
- medial vestibular nucleus
- paraventricular nucleus of hypothalamus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/6/6a/PBB_GE_CHD5_213965_s_at_fs.png/250px-PBB_GE_CHD5_213965_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/PBB_GE_CHD5_217250_s_at_fs.png/250px-PBB_GE_CHD5_217250_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- nucleotide binding
- helicase activity
- metal ion binding
- H3K27me3 modified histone binding
- hydrolase activity
- ATP binding
| Cellular component | - NuRD complex
- membrane
- heterochromatin
- nucleus
- nucleoplasm
- cytosol
- nuclear speck
| Biological process | - cell differentiation
- regulation of transcription, DNA-templated
- histone H3-K27 trimethylation
- positive regulation of signal transduction by p53 class mediator
- transcription, DNA-templated
- nervous system development
- spermatogenesis
- histone H4 acetylation
- cerebral cortex neuron differentiation
- negative regulation of cell population proliferation
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001081376 NM_029216 NM_001369243 |
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RefSeq (protein) | | |
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NP_001074845 NP_083492 NP_001356172 |
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Location (UCSC) | Chr 1: 6.1 – 6.18 Mb | Chr 4: 152.42 – 152.47 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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