CHD9

Protein-coding gene in the species Homo sapiens
CHD9
Identifiers
AliasesCHD9, AD013, CReMM, KISH2, PRIC320, CHD-9, chromodomain helicase DNA binding protein 9
External IDsOMIM: 616936; MGI: 1924001; HomoloGene: 11844; GeneCards: CHD9; OMA:CHD9 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for CHD9
Genomic location for CHD9
Band16q12.2Start53,054,991 bp[1]
End53,329,150 bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for CHD9
Genomic location for CHD9
Band8|8 C4Start91,554,980 bp[2]
End91,781,144 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • tibia

  • mucosa of paranasal sinus

  • tendon of biceps brachii

  • skin of hip

  • visceral pleura

  • renal medulla

  • urethra

  • pylorus

  • corpus callosum
Top expressed in
  • right kidney

  • esophagus

  • lip

  • hand

  • aortic valve

  • zygote

  • ascending aorta

  • otolith organ

  • utricle

  • secondary oocyte
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • DNA binding
  • nucleotide binding
  • hydrolase activity, acting on acid anhydrides
  • protein binding
  • ATP binding
  • hydrolase activity
  • helicase activity
Cellular component
  • nucleoplasm
  • nucleus
  • cytoplasm
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of lipid metabolic process
  • chromatin organization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

80205

109151

Ensembl

ENSG00000177200

ENSMUSG00000056608

UniProt

Q3L8U1

Q8BYH8

RefSeq (mRNA)
NM_001308319
NM_015287
NM_025134
NM_001352127
NM_001352156

NM_001352157
NM_001352158
NM_001382353
NM_001382354
NM_001382355

NM_177224
NM_001310530

RefSeq (protein)
NP_001295248
NP_079410
NP_001339056
NP_001339085
NP_001339086

NP_001339087
NP_001369282
NP_001369283
NP_001369284

NP_001297459
NP_796198

Location (UCSC)Chr 16: 53.05 – 53.33 MbChr 8: 91.55 – 91.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chromodomain-helicase-DNA-binding protein 9 is an enzyme that in humans is encoded by the CHD9 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000177200 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056608 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" (PDF). DNA Research. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
  6. ^ "Entrez Gene: CHD9 chromodomain helicase DNA binding protein 9".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (Aug 2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proceedings of the National Academy of Sciences of the United States of America. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Shur I, Benayahu D (Sep 2005). "Characterization and functional analysis of CReMM, a novel chromodomain helicase DNA-binding protein". Journal of Molecular Biology. 352 (3): 646–55. doi:10.1016/j.jmb.2005.06.049. PMID 16095617.
  • Marom R, Shur I, Hager GL, Benayahu D (Jun 2006). "Expression and regulation of CReMM, a chromodomain helicase-DNA-binding (CHD), in marrow stroma derived osteoprogenitors". Journal of Cellular Physiology. 207 (3): 628–35. doi:10.1002/jcp.20611. PMID 16523501. S2CID 21524910.
  • Surapureddi S, Viswakarma N, Yu S, Guo D, Rao MS, Reddy JK (May 2006). "PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex". Biochemical and Biophysical Research Communications. 343 (2): 535–43. doi:10.1016/j.bbrc.2006.02.160. PMID 16554032.
  • Shur I, Solomon R, Benayahu D (May 2006). "Dynamic interactions of chromatin-related mesenchymal modulator, a chromodomain helicase-DNA-binding protein, with promoters in osteoprogenitors". Stem Cells. 24 (5): 1288–93. doi:10.1634/stemcells.2005-0300. PMID 16705189. S2CID 24621014.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.


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