CHMP4C |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | CHMP4C, SNF7-3, Shax3, VPS32C, charged multivesicular body protein 4C |
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External IDs | OMIM: 610899; MGI: 1913621; HomoloGene: 23544; GeneCards: CHMP4C; OMA:CHMP4C - orthologs |
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Gene location (Human) |
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![Chromosome 8 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/300px-Ideogram_human_chromosome_8.svg.png) | Chr. | Chromosome 8 (human)[1] |
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| Band | 8q21.13 | Start | 81,732,448 bp[1] |
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End | 81,759,515 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 A1 | Start | 10,431,967 bp[2] |
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End | 10,493,916 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - amniotic fluid
- jejunal mucosa
- mucosa of ileum
- skin of arm
- palpebral conjunctiva
- parotid gland
- duodenum
- pancreatic epithelial cell
- gingival epithelium
- mucosa of colon
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| Top expressed in | - interventricular septum
- ileum
- duodenum
- jejunum
- epithelium of stomach
- Paneth cell
- left colon
- ascending aorta
- parotid gland
- epithelium of small intestine
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/32/PBB_GE_CHMP4C_gnf1h06239_at_fs.png/250px-PBB_GE_CHMP4C_gnf1h06239_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein homodimerization activity
- protein binding
| Cellular component | - cytoplasm
- ESCRT III complex
- cytosol
- endosome
- membrane
- late endosome membrane
- midbody
- Flemming body
| Biological process | - regulation of centrosome duplication
- abscission
- viral budding via host ESCRT complex
- viral life cycle
- nucleus organization
- multivesicular body assembly
- regulation of mitotic spindle assembly
- endosomal transport
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
- protein transport
- negative regulation of cytokinesis
- septum digestion after cytokinesis
- mitotic metaphase plate congression
- vacuolar transport
- macroautophagy
- mitotic cytokinesis checkpoint signaling
- midbody abscission
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 8: 81.73 – 81.76 Mb | Chr 3: 10.43 – 10.49 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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