CLDN12

Protein-coding gene in the species Homo sapiens

CLDN12

Identifiers

Aliases

CLDN12, claudin 12

External IDs

OMIM: 611232; MGI: 1929288; HomoloGene: 40809; GeneCards: CLDN12; OMA:CLDN12 - orthologs

Gene location (Human)

Chr.	Chromosome 7 (human)^[1]

Band	7q21.13	Start	90,383,721 bp^[1]
Band	7q21.13	End	90,513,402 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	5\|5 A1	Start	5,539,537 bp^[2]
Band	5\|5 A1	End	5,564,958 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

secondary oocyte

islet of Langerhans

pancreatic epithelial cell

cartilage tissue

mucosa of sigmoid colon

right lobe of liver

rectum

pituitary gland

anterior pituitary

myocardium of left ventricle

Top expressed in

otolith organ

utricle

interventricular septum

retinal pigment epithelium

ascending aorta

supraoptic nucleus

ciliary body

primitive streak

aortic valve

epithelium of lens

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	structural molecule activity identical protein binding protein binding
Cellular component	integral component of membrane cell junction lateral plasma membrane membrane cell periphery bicellular tight junction plasma membrane
Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


9069


64945

Ensembl


ENSG00000157224


ENSMUSG00000046798

UniProt


P56749


Q9ET43

RefSeq (mRNA)


NM_012129 NM_001185072 NM_001185073


NM_001193659 NM_001193660 NM_001193661 NM_022890

RefSeq (protein)


NP_001172001 NP_001172002 NP_036261


NP_001180588 NP_001180589 NP_001180590 NP_075028

Location (UCSC)

Chr 7: 90.38 – 90.51 Mb

Chr 5: 5.54 – 5.56 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Claudin-12 is a protein that in humans is encoded by the CLDN12 gene.^[5] It belongs to the group of claudins.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157224 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000046798 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CLDN12 claudin 12".

External links

Human CLDN12 genome location and CLDN12 gene details page in the UCSC Genome Browser.

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