CNTLN

Protein-coding gene in the species Homo sapiens
CNTLN
Identifiers
AliasesCNTLN, C9orf101, C9orf39, bA340N12.1, centlein
External IDsOMIM: 611870; MGI: 2443104; HomoloGene: 9805; GeneCards: CNTLN; OMA:CNTLN - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for CNTLN
Genomic location for CNTLN
Band9p22.2Start17,134,982 bp[1]
End17,503,923 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for CNTLN
Genomic location for CNTLN
Band4|4 C4Start84,802,546 bp[2]
End85,050,158 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • buccal mucosa cell

  • Achilles tendon

  • ventricular zone

  • gonad

  • sural nerve

  • ganglionic eminence

  • testicle

  • monocyte

  • secondary oocyte

  • right lobe of liver
Top expressed in
  • saccule

  • zygote

  • spermatocyte

  • otic vesicle

  • genital tubercle

  • secondary oocyte

  • ventricular zone

  • vas deferens

  • sciatic nerve

  • iris
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein-macromolecule adaptor activity
  • protein kinase binding
  • protein domain specific binding
Cellular component
  • cytoplasm
  • centriole
  • extracellular exosome
  • cytoskeleton
  • nucleoplasm
  • centrosome
  • cytosol
Biological process
  • protein localization to organelle
  • centriole-centriole cohesion
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54875

338349

Ensembl

ENSG00000044459

ENSMUSG00000038070

UniProt

Q9NXG0

A2AM05

RefSeq (mRNA)

NM_001114395
NM_001286984
NM_001286985
NM_017738
NM_001365029

NM_175275
NM_177385

RefSeq (protein)

NP_001107867
NP_001273913
NP_001273914
NP_060208
NP_001351958

NP_780484
NP_796359
NP_001392359
NP_001392360

Location (UCSC)Chr 9: 17.13 – 17.5 MbChr 4: 84.8 – 85.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centlein, centrosomal protein is a protein in humans that is encoded by the CNTLN gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000044459 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038070 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Centlein, centrosomal protein".

Further reading

  • Makino K, Umeda K, Uezu A, Hiragami Y, Sakamoto T, Ihn H, Nakanishi H (February 2008). "Identification and characterization of the novel centrosomal protein centlein". Biochemical and Biophysical Research Communications. 366 (4): 958–62. doi:10.1016/j.bbrc.2007.12.050. PMID 18086554.
  • Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, et al. (September 2009). "A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2". Nature Genetics. 41 (9): 996–1000. doi:10.1038/ng.424. PMC 2844110. PMID 19648919.
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