CREBRF

Protein-coding gene in the species Homo sapiens
CREBRF
Identifiers
AliasesCREBRF, C5orf41, LRF, CREB3 regulatory factor
External IDsOMIM: 617109; MGI: 1924378; HomoloGene: 12672; GeneCards: CREBRF; OMA:CREBRF - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for CREBRF
Genomic location for CREBRF
Band5q35.1Start173,056,352 bp[1]
End173,139,284 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for CREBRF
Genomic location for CREBRF
Band17|17 A3.3Start26,715,650 bp[2]
End26,776,635 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • superficial temporal artery

  • synovial membrane

  • internal globus pallidus

  • lower lobe of lung

  • urethra

  • bone marrow cells

  • cardiac muscle tissue of right atrium

  • caput epididymis

  • tail of epididymis
Top expressed in
  • vestibular membrane of cochlear duct

  • ciliary body

  • spermatocyte

  • dorsomedial hypothalamic nucleus

  • iris

  • carotid body

  • spermatid

  • retinal pigment epithelium

  • Epithelium of choroid plexus

  • suprachiasmatic nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • protein binding
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding
  • DNA-binding transcription activator activity, RNA polymerase II-specific
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • cytoplasm
  • nuclear body
  • nucleus
  • nucleoplasm
Biological process
  • negative regulation of endoplasmic reticulum unfolded protein response
  • positive regulation of prolactin signaling pathway
  • response to unfolded protein
  • regulation of transcription, DNA-templated
  • negative regulation of transcription by RNA polymerase II
  • positive regulation of protein catabolic process
  • maternal behavior
  • negative regulation of glucocorticoid mediated signaling pathway
  • positive regulation of intracellular transport
  • transcription, DNA-templated
  • response to endoplasmic reticulum stress
  • positive regulation of protein transport
  • endoplasmic reticulum unfolded protein response
  • transcription by RNA polymerase II
  • positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

153222

77128

Ensembl

ENSG00000164463

ENSMUSG00000048249

UniProt

Q8IUR6

Q8CDG5

RefSeq (mRNA)

NM_001168393
NM_001168394
NM_153607

NM_029870

RefSeq (protein)

NP_001161865
NP_001161866
NP_705835

NP_084146

Location (UCSC)Chr 5: 173.06 – 173.14 MbChr 17: 26.72 – 26.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CREB3 regulatory factor is a protein that in humans is encoded by the CREBRF gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164463 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048249 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CREB3 regulatory factor". Retrieved 2016-10-08.

Further reading


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