DEPDC1

DEPDC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YSR
Identifiers
Aliases	DEPDC1, DEP.8, DEPDC1-V2, DEPDC1A, SDP35, DEP domain containing 1
External IDs	OMIM: 612002; MGI: 1923381; HomoloGene: 9834; GeneCards: DEPDC1; OMA:DEPDC1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p31.3 Start 68,474,152 bp[1] End 68,497,221 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 H4 Start 159,201,070 bp[2] End 159,235,592 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone gonad testicle trabecular bone sperm ganglionic eminence stromal cell of endometrium bone marrow rectum mucosa of ileum Top expressed in genital tubercle tail of embryo upper arm mesenchyme epiblast spinal ganglia thymus ventricular zone bone marrow peripheral nervous system More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding GTPase activator activity Cellular component transcription repressor complex nucleus Biological process positive regulation of GTPase activity intracellular signal transduction negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55635 76131 Ensembl ENSG00000024526 ENSMUSG00000028175 UniProt Q5TB30 Q8CIG0 RefSeq (mRNA) NM_017779 NM_001114120 NM_001172092 NM_001172093 NM_029523 RefSeq (protein) NP_001107592 NP_060249 NP_001165563 NP_001165564 NP_083799 Location (UCSC) Chr 1: 68.47 – 68.5 Mb Chr 3: 159.2 – 159.24 Mb PubMed search [3] [4]
Wikidata
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DEP domain containing 1 is a protein in humans that is encoded by the DEPDC1 gene. ^[5]

• PDBe-KB provides an overview of all the structure information available in the PDB for Human DEP domain-containing protein 1A (DEPDC1)