DUSP18 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Protein_DUSP18_PDB_2esb.png/250px-Protein_DUSP18_PDB_2esb.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | DUSP18, DSP18, DUSP20, LMWDSP20, bK963H5.1, dual specificity phosphatase 18 |
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External IDs | OMIM: 611446; MGI: 1922469; HomoloGene: 34984; GeneCards: DUSP18; OMA:DUSP18 - orthologs |
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Gene location (Human) |
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![Chromosome 22 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/62/Ideogram_human_chromosome_22.svg/300px-Ideogram_human_chromosome_22.svg.png) | Chr. | Chromosome 22 (human)[1] |
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| Band | 22q12.2 | Start | 30,652,051 bp[1] |
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End | 30,667,887 bp[1] |
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Gene location (Mouse) |
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![Chromosome 11 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/a/a5/Ideogram_house_mouse_chromosome_11.svg/260px-Ideogram_house_mouse_chromosome_11.svg.png) | Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 A1 | Start | 3,845,240 bp[2] |
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End | 3,851,296 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- bronchial epithelial cell
- mucosa of ileum
- left testis
- right testis
- testicle
- mucosa of paranasal sinus
- sperm
- right uterine tube
- blood
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| Top expressed in | - zygote
- interventricular septum
- secondary oocyte
- myocardium of ventricle
- Rostral migratory stream
- dentate gyrus of hippocampal formation granule cell
- lip
- islet of Langerhans
- soleus muscle
- muscle of thigh
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/8/84/PBB_GE_DUSP18_gnf1h07693_at_fs.png/250px-PBB_GE_DUSP18_gnf1h07693_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein tyrosine phosphatase activity
- MAP kinase tyrosine/serine/threonine phosphatase activity
- phosphoprotein phosphatase activity
- hydrolase activity
- phosphatase activity
- protein tyrosine/serine/threonine phosphatase activity
| Cellular component | - cytoplasm
- nucleus
- nucleoplasm
- mitochondrion
- membrane
- mitochondrial inner membrane
| Biological process | - protein dephosphorylation
- peptidyl-tyrosine dephosphorylation
- peptidyl-threonine dephosphorylation
- dephosphorylation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001304794 NM_001304795 NM_001304796 NM_152511 |
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RefSeq (protein) | |
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NP_001291723 NP_001291724 NP_001291725 NP_689724 |
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Location (UCSC) | Chr 22: 30.65 – 30.67 Mb | Chr 11: 3.85 – 3.85 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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