Dermal cylindroma

Medical condition
Dermal cylindroma
Dermal cylindroma treated with X-rays without recurrence

In dermatologic pathology, a dermal cylindroma, also dermal eccrine cylindroma or cutaneous cylindroma[1]: 666 ) and (less specifically) cylindroma, is a benign adnexal tumor[2] that occurs on the scalp and forehead.

Multiple cylindromas may grow together in a "hat-like" configuration, sometimes referred to as a turban tumor.[3] Cylindromas are uncommon dysplasias of skin appendages.[4]

Histology

Dermal cylindromas are:

  • Dermal lesions consisting of nests of cells that are surrounded by hyaline (i.e., glassy, eosinophilic, acellular) material and have:
    • Hyperchromatic nuclei that may palisade (columnar nuclei arranged around the periphery of the cell nests with their short axis tangential to the nest periphery), and
    • Cells with lighter staining ovoid nuclei at their centre.

They lack of a significant number of lymphocytes; this differentiates them from spiradenomas.

Additional images

  • Micrograph of a dermal cylindroma in H&E stain.
    Micrograph of a dermal cylindroma in H&E stain.
  • Micrograph of dermal cylindroma in H&E stain.
    Micrograph of dermal cylindroma in H&E stain.
  • Dermal cylindroma. Puzzle-like distribution of tumour foci.
    Dermal cylindroma. Puzzle-like distribution of tumour foci.
  • Dermal cylindroma. Hyaline droplets visible in lobules.
    Dermal cylindroma. Hyaline droplets visible in lobules.
  • Dermal cylindroma, micronodular type.
    Dermal cylindroma, micronodular type.

See also

  • Spiradenoma
  • Malignant acrospiroma

References

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ "Cylindroma" at Dorland's Medical Dictionary
  3. ^ "Cylindroma: Background, Pathophysiology, Epidemiology". 14 July 2021.
  4. ^ Cylindroma at eMedicine
Classification
D
  • ICD-O: M8200/3
  • MeSH: D003528
External resources
  • eMedicine: derm/94
  • v
  • t
  • e
Glandular and epithelial cancer
Epithelium
Papilloma/carcinoma
Complex epithelial
Glands
Adenomas/
adenocarcinomas
Gastrointestinal
Urogenital
Endocrine
Other/multiple
Adnexal and
skin appendage
Cystic,
mucinous,
and serous
Cystic general
Mucinous
Serous
Ductal,
lobular,
and medullary
Ductal carcinoma
Lobular carcinoma
Medullary carcinoma
Acinar cell
  • v
  • t
  • e
Glands
Sweat gland
Eccrine
Apocrine
Eccrine/apocrine
Sebaceous gland
Hair
Hamartoma
Nails