Dibromotyrosine
Chemical compound
- H03BX02 (WHO)
- (2S)-2-Amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid
- 300-38-9 Y
- 67532
- 60854 N
- QD49LEP46E
- CHEBI:28335 N
- ChEMBL1232132 N
- DTXSID401015579
- Interactive image
- Brc1cc(cc(Br)c1O)C[C@@H](C(=O)O)N
InChI
- InChI=1S/C9H9Br2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1 N
- Key:COESHZUDRKCEPA-ZETCQYMHSA-N N
Dibromotyrosine is an antithyroid preparation and a derivative of the natural amino acid tyrosine.
It is formed by eosinophil peroxidase.[1]
References
- ^ Kambayashi Y, Ogino K, Takemoto K, et al. (January 2009). "Preparation and Characterization of a Polyclonal Antibody against Brominated Protein". J Clin Biochem Nutr. 44 (1): 95–103. doi:10.3164/jcbn.08-196. PMC 2613505. PMID 19177194.
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Thyroid therapy (H03)
Thyroid peroxidase inhibitors (thioamide) | |
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Block conversion of T4 to T3 | |
Sodium-iodide symporter inhibitor | |
Other |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This hormonal preparation article is a stub. You can help Wikipedia by expanding it. |
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