FAM172A

Protein-coding gene in the species Homo sapiens
FAM172A
Identifiers
AliasesFAM172A, C5orf21, family with sequence similarity 172 member A, Toupee
External IDsMGI: 1915925; HomoloGene: 12933; GeneCards: FAM172A; OMA:FAM172A - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for FAM172A
Genomic location for FAM172A
Band5q15Start93,617,725 bp[1]
End94,111,699 bp[1]
Gene location (Mouse)
Chromosome 13 (mouse)
Chr.Chromosome 13 (mouse)[2]
Chromosome 13 (mouse)
Genomic location for FAM172A
Genomic location for FAM172A
Band13|13 C1Start77,850,152 bp[2]
End78,314,354 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • Achilles tendon

  • tendon of biceps brachii

  • caput epididymis

  • optic nerve

  • epithelium of colon

  • corpus epididymis

  • paraflocculus of cerebellum

  • tail of epididymis

  • bronchial epithelial cell

  • stromal cell of endometrium
Top expressed in
  • spermatocyte

  • zygote

  • medial ganglionic eminence

  • Region I of hippocampus proper

  • superior cervical ganglion

  • ventricular zone

  • secondary oocyte

  • genital tubercle

  • thymus

  • hand
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • siRNA binding
Cellular component
  • endoplasmic reticulum
  • extracellular region
  • nucleus
  • cytoplasm
Biological process
  • regulation of alternative mRNA splicing, via spliceosome
  • neural crest cell development
  • mRNA processing
  • RNA splicing
  • heterochromatin assembly by small RNA
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83989

68675

Ensembl

ENSG00000113391

ENSMUSG00000064138

UniProt

Q8WUF8

Q3TNH5

RefSeq (mRNA)

NM_001163417
NM_001163418
NM_032042

NM_001163419
NM_001163420
NM_138312

RefSeq (protein)

NP_001156889
NP_001156890
NP_114431

NP_001156891
NP_001156892
NP_612185

Location (UCSC)Chr 5: 93.62 – 94.11 MbChr 13: 77.85 – 78.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

UPF0528 protein FAM172A is a protein that in humans is encoded by the FAM172A gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113391 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000064138 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ "Entrez Gene: C5orf21 chromosome 5 open reading frame 21".

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.


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