FAM20B

Protein-coding gene in the species Homo sapiens
FAM20B
Identifiers
AliasesFAM20B, gxk1, family with sequence similarity 20 member B, glycosaminoglycan xylosylkinase, FAM20B glycosaminoglycan xylosylkinase
External IDsOMIM: 611063; MGI: 2443990; HomoloGene: 8909; GeneCards: FAM20B; OMA:FAM20B - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for FAM20B
Genomic location for FAM20B
Band1q25.2Start179,025,804 bp[1]
End179,076,567 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for FAM20B
Genomic location for FAM20B
Band1|1 G3Start156,506,102 bp[2]
End156,546,656 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lateral nuclear group of thalamus

  • Brodmann area 10

  • saphenous vein

  • external globus pallidus

  • Pars compacta

  • pars reticulata

  • frontal pole

  • spinal ganglia

  • tail of epididymis

  • trigeminal ganglion
Top expressed in
  • Paneth cell

  • ciliary body

  • retinal pigment epithelium

  • transitional epithelium of urinary bladder

  • saccule

  • ileum

  • crypt of lieberkuhn of small intestine

  • central gray substance of midbrain

  • left colon

  • ectoderm
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • transferase activity
  • nucleotide binding
  • ATP binding
  • metal ion binding
  • phosphotransferase activity, alcohol group as acceptor
  • kinase activity
  • protein binding
Cellular component
  • integral component of membrane
  • Golgi membrane
  • Golgi apparatus
  • membrane
  • nucleoplasm
Biological process
  • phosphorylation
  • protein phosphorylation
  • proteoglycan biosynthetic process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9917

215015

Ensembl

ENSG00000116199

ENSMUSG00000033557

UniProt

O75063

Q8VCS3

RefSeq (mRNA)

NM_014864
NM_001324310
NM_001324311

NM_145413

RefSeq (protein)

NP_001311239
NP_001311240
NP_055679

NP_663388

Location (UCSC)Chr 1: 179.03 – 179.08 MbChr 1: 156.51 – 156.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein FAM20B is a protein that in humans is encoded by the FAM20B gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116199 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033557 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.
  6. ^ "Entrez Gene: FAM20B family with sequence similarity 20, member B".

Further reading

  • Baxendale HE, Goldblatt D (2006). "Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies". Infect. Immun. 74 (2): 1025–1031. doi:10.1128/IAI.74.2.1025-1031.2006. PMC 1360365. PMID 16428749.
  • Nalbant D, Youn H, Nalbant SI, et al. (2006). "FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells". BMC Genomics. 6: 11. doi:10.1186/1471-2164-6-11. PMC 548683. PMID 15676076.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Yavuz S, Grammer AC, Yavuz AS, et al. (2001). "Comparative characteristics of mu chain and alpha chain transcripts expressed by individual tonsil plasma cells". Mol. Immunol. 38 (1): 19–34. doi:10.1016/S0161-5890(01)00036-0. PMID 11483207.
  • Baxendale HE, Davis Z, White HN, et al. (2000). "Immunogenetic analysis of the immune response to pneumococcal polysaccharide". Eur. J. Immunol. 30 (4): 1214–1223. doi:10.1002/(SICI)1521-4141(200004)30:4<1214::AID-IMMU1214>3.0.CO;2-D. PMID 10760811. S2CID 30848617.
  • Ishikawa K, Nagase T, Nakajima D, et al. (1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–313. doi:10.1093/dnares/4.5.307. PMID 9455477.
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