Protein-coding gene in the species Homo sapiens
| FJX1 |
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| Identifiers |
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| Aliases | FJX1, four jointed box 1, four-jointed box kinase 1 |
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| External IDs | OMIM: 612206; MGI: 1341907; HomoloGene: 7717; GeneCards: FJX1; OMA:FJX1 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 11 (human)[1] |
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| | Band | 11p13 | Start | 35,618,460 bp[1] |
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| End | 35,620,865 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 2 (mouse)[2] |
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| | Band | 2|2 E2 | Start | 102,279,711 bp[2] |
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| End | 102,282,844 bp[2] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - ventricular zone
- ganglionic eminence
- Brodmann area 23
- testicle
- gonad
- middle temporal gyrus
- gingival epithelium
- anterior cingulate cortex
- stromal cell of endometrium
- nucleus accumbens
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| | Top expressed in | - subiculum
- lumbar subsegment of spinal cord
- molar
- olfactory bulb
- olfactory tubercle
- medial geniculate nucleus
- prefrontal cortex
- anterior amygdaloid area
- corneal stroma
- medial dorsal nucleus
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| | More reference expression data |
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| BioGPS | |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 11: 35.62 – 35.62 Mb | Chr 2: 102.28 – 102.28 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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Four jointed box 1 is a protein that in humans is encoded by the FJX1 gene. [5]
Function
The protein encoded by this gene is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000179431 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075012 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Four jointed box 1". Retrieved 2015-09-17.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
