GFRAL |
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Identifiers |
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Aliases | GFRAL, C6orf144, GRAL, UNQ9356, bA360D14.1, GDNF family receptor alpha like |
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External IDs | OMIM: 617837; MGI: 3607786; HomoloGene: 45748; GeneCards: GFRAL; OMA:GFRAL - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6p12.1 | Start | 55,327,469 bp[1] |
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End | 55,402,493 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 D | Start | 76,071,384 bp[2] |
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End | 76,120,939 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - testicle
- sural nerve
- right lobe of liver
- subcutaneous adipose tissue
- body of pancreas
- lactiferous gland
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - signaling receptor activity
- protein binding
- glial cell-derived neurotrophic factor receptor activity
- receptor tyrosine kinase binding
| Cellular component | - integral component of membrane
- plasma membrane
- intracellular anatomical structure
- membrane
- external side of plasma membrane
- receptor complex
| Biological process | - negative regulation of neuron apoptotic process
- stress-activated protein kinase signaling cascade
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
- reduction of food intake in response to dietary excess
- glial cell-derived neurotrophic factor receptor signaling pathway
- positive regulation of MAPK cascade
- positive regulation of protein kinase B signaling
- nervous system development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 55.33 – 55.4 Mb | Chr 9: 76.07 – 76.12 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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