Gastric atresia
Congenital disorder of the digestive system
Gastric atresia is a congenital defect with complete occlusion of the pyloric outlet of the stomach.[1]
Cause
Gastric atresia is a birth defect. It can be genetic, inherited in an autosomal recessive manner, and associated with conditions like Down syndrome and junctional epidermolysis bullosa (medicine).[2] In about 60% of cases, the outlet of the stomach is covered by a membrane. In around 35% of cases, solid tissue blocks the outlet. In the remaining cases (less than 10%), there is a complete separation of the stomach and the small intestine.[3]
Diagnosis
Polyhydramnios is often seen during pregnancy, and prenatal diagnosis is common.[3] Infants with gastric atresia will exhibit forceful vomiting upon the first feeding. Imaging is required for diagnosis.[2]
Treatment
Treatment is surgical and involves removing or bypassing the obstruction.[2][3]
Epidemiology
It is seen in approximately 1 in 100,000 live births.[4]
References
- ^ Wurtenberger, H. (1 April 1961). "Gastric Atresia". Archives of Disease in Childhood. 36 (186): 161–163. doi:10.1136/adc.36.186.161. PMC 2012745. PMID 13786876.
- ^ a b c Feldman, Mark (2016). Sleisenger and Fordtran's Gastrointestinal and Liver Disease (10 ed.). Elsevier. pp. 801–803.
- ^ a b c Avery's Diseases of the Newborn (10 ed.). Elsevier. 2018. pp. 1039–1053.
- ^ Fetal and Neonatal Physiology (5 ed.). Elsevier. 2017. pp. 861–870.
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Congenital malformations and deformations of digestive system
| Tongue, mouth and pharynx |
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| Esophagus |
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| Stomach |
| Intestines | |
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| Rectum/anal canal |
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| Pancreas | |
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| Bile duct | |
| Liver |
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