INTS9

Protein-coding gene in the species Homo sapiens
INTS9
Identifiers
AliasesINTS9, CPSF2L, INT9, RC74, integrator complex subunit 9
External IDsOMIM: 611352; MGI: 1098533; HomoloGene: 10096; GeneCards: INTS9; OMA:INTS9 - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for INTS9
Genomic location for INTS9
Band8p21.1Start28,767,661 bp[1]
End28,890,242 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for INTS9
Genomic location for INTS9
Band14 D1|14 33.81 cMStart65,187,494 bp[2]
End65,277,284 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • right adrenal gland

  • right adrenal cortex

  • left adrenal gland

  • left adrenal cortex

  • apex of heart

  • gonad

  • testicle

  • granulocyte

  • buccal mucosa cell
Top expressed in
  • primary oocyte

  • tail of embryo

  • genital tubercle

  • maxillary prominence

  • epiblast

  • secondary oocyte

  • mandibular prominence

  • ankle joint

  • zygote

  • internal carotid artery
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • integrator complex
  • nucleoplasm
  • cytosol
  • nucleus
Biological process
  • snRNA processing
  • snRNA transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55756

210925

Ensembl

ENSG00000104299

ENSMUSG00000021975

UniProt

Q9NV88

Q8K114

RefSeq (mRNA)

NM_001145159
NM_001172562
NM_018250
NM_001363038

NM_001253731
NM_153414

RefSeq (protein)

NP_001138631
NP_001166033
NP_060720
NP_001349967

NP_001240660
NP_700463

Location (UCSC)Chr 8: 28.77 – 28.89 MbChr 14: 65.19 – 65.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Integrator complex subunit 9 is a protein that in Humans is encoded by the INTS9 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000104299 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021975 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.
  6. ^ "Entrez Gene: RC74 integrator complex subunit 9".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Dominski Z, Yang XC, Purdy M, et al. (2005). "A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100". Mol. Cell. Biol. 25 (4): 1489–500. doi:10.1128/MCB.25.4.1489-1500.2005. PMC 548002. PMID 15684398.
  • Nusbaum C, Mikkelsen TS, Zody MC, et al. (2006). "DNA sequence and analysis of human chromosome 8". Nature. 439 (7074): 331–5. Bibcode:2006Natur.439..331N. doi:10.1038/nature04406. PMID 16421571.


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