IQCE

Protein-coding gene in the species Homo sapiens
IQCE
Identifiers
AliasesIQCE, 1700028P05Rik, IQ motif containing E, PAPA7
External IDsOMIM: 617631; MGI: 1921489; HomoloGene: 49912; GeneCards: IQCE; OMA:IQCE - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for IQCE
Genomic location for IQCE
Band7p22.3Start2,558,972 bp[1]
End2,614,733 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for IQCE
Genomic location for IQCE
Band5|5 G2Start140,647,582 bp[2]
End140,688,133 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • sural nerve

  • bronchial epithelial cell

  • right uterine tube

  • mucosa of paranasal sinus

  • olfactory zone of nasal mucosa

  • C1 segment

  • pituitary gland

  • anterior pituitary
Top expressed in
  • spermatid

  • spermatocyte

  • otolith organ

  • utricle

  • hand

  • neural layer of retina

  • otic vesicle

  • internal carotid artery

  • seminiferous tubule

  • external carotid artery
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • cilium
  • plasma membrane
  • membrane
  • cell projection
  • ciliary membrane
Biological process
  • limb morphogenesis
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23288

74239

Ensembl

ENSG00000106012

ENSMUSG00000036555

UniProt

Q6IPM2

Q6PCQ0

RefSeq (mRNA)
NM_001100390
NM_001287499
NM_001287500
NM_001287501
NM_001287502

NM_152558

NM_028833
NM_001347517

RefSeq (protein)

NP_001274428
NP_001274429
NP_001274430
NP_001274431
NP_689771

NP_001334446
NP_083109

Location (UCSC)Chr 7: 2.56 – 2.61 MbChr 5: 140.65 – 140.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

IQ domain-containing protein E is a protein that in humans is encoded by the IQCE gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106012 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036555 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
  6. ^ "Entrez Gene: IQCE IQ motif containing E".
  • Umair M, Shah K, Alhaddad B, Haack TB, Graf E, Strom TM, Meitinger T, Ahmad W (2017). "Exome sequencing revealed a splice site variant in the IQCE gene underlying post-axial polydactyly type A restricted to lower limb". Eur J Hum Genet. 25 (8): 960–965. doi:10.1038/ejhg.2017.83. PMC 5567151. PMID 28488682.

Further reading

  • Umair M, Shah K, Alhaddad B, Haack TB, Graf E, Strom TM, Meitinger T, Ahmad W (2017). "Exome sequencing revealed a splice site variant in the IQCE gene underlying post-axial polydactyly type A restricted to lower limb". Eur J Hum Genet. 25 (8): 960–965. doi:10.1038/ejhg.2017.83. PMC 5567151. PMID 28488682.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.


  • v
  • t
  • e