Protein-coding gene in the species Homo sapiens
| ITLN2 |
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| Identifiers |
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| Aliases | ITLN2, HL-2, HL2, intelectin 2 |
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| External IDs | OMIM: 609874; HomoloGene: 135852; GeneCards: ITLN2; OMA:ITLN2 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 1 (human)[1] |
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| | Band | 1q23.3 | Start | 160,945,025 bp[1] |
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| End | 160,954,809 bp[1] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - duodenum
- right lung
- upper lobe of left lung
- right coronary artery
- gonad
- left coronary artery
- left ovary
- right ovary
- right auricle
- rectum
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| | | More reference expression data |
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| BioGPS | |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 1: 160.95 – 160.95 Mb | n/a |
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| PubMed search | [2] | n/a |
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| Wikidata |
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Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.[3]
Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.[4]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000158764 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Intelectin 2". Retrieved 2016-02-25.
- ^ Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT (March 2016). "Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition". The Journal of Biological Chemistry. 291 (11): 5596–610. doi:10.1074/jbc.M115.709212. PMC 4786701. PMID 26755729.
