KDM7A |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78 |
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Identifiers |
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Aliases | KDM7A, JHDM1D, lysine demethylase 7A |
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External IDs | MGI: 2443388; HomoloGene: 25281; GeneCards: KDM7A; OMA:KDM7A - orthologs |
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Gene location (Human) |
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![Chromosome 7 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/9/99/Ideogram_human_chromosome_7.svg/300px-Ideogram_human_chromosome_7.svg.png) | Chr. | Chromosome 7 (human)[1] |
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| Band | 7q34 | Start | 140,084,746 bp[1] |
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End | 140,176,983 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 B1 | Start | 39,113,557 bp[2] |
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End | 39,183,723 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - cartilage tissue
- tendon of biceps brachii
- glutes
- bone marrow
- skin of thigh
- epithelium of nasopharynx
- monocyte
- buccal mucosa cell
- skin of hip
- bone marrow cells
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| Top expressed in | - blood
- zygote
- granulocyte
- Rostral migratory stream
- vestibular sensory epithelium
- secondary oocyte
- left lung lobe
- mesenteric lymph nodes
- lobe of cerebellum
- cerebellar vermis
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - 2-oxoglutarate-dependent dioxygenase activity
- iron ion binding
- histone H3-methyl-lysine-9 demethylase activity
- histone H4-methyl-lysine-20 demethylase activity
- dioxygenase activity
- metal ion binding
- methylated histone binding
- histone H3-methyl-lysine-36 demethylase activity
- oxidoreductase activity
- histone H3-tri/di-methyl-lysine-27 demethylase activity
- histone demethylase activity
- zinc ion binding
| Cellular component | - nucleoplasm
- nucleolus
- nucleus
| Biological process | - regulation of transcription, DNA-templated
- histone H3-K27 demethylation
- histone H3-K9 demethylation
- histone H4-K20 demethylation
- transcription, DNA-templated
- nervous system development
- positive regulation of transcription, DNA-templated
- histone H3-K36 demethylation
- midbrain development
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 7: 140.08 – 140.18 Mb | Chr 6: 39.11 – 39.18 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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