L3MBTL2

Protein-coding gene in the species Homo sapiens

L3MBTL2

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
2W0T, 3CEY, 3F70

Identifiers

Aliases

L3MBTL2, H-l(3)mbt-l, L3MBT, L3MBTL2 polycomb repressive complex 1 subunit, polycomb repressive complex 1 subunit, L3MBTL histone methyl-lysine binding protein 2

External IDs

OMIM: 611865; MGI: 2443584; HomoloGene: 12882; GeneCards: L3MBTL2; OMA:L3MBTL2 - orthologs

Gene location (Human)

Chr.	Chromosome 22 (human)^[1]

Band	22q13.2	Start	41,205,282 bp^[1]
Band	22q13.2	End	41,231,271 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 15 (mouse)^[2]

Band	15\|15 E1	Start	81,548,090 bp^[2]
Band	15\|15 E1	End	81,572,516 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

pancreatic ductal cell

tibialis anterior muscle

parotid gland

nasal epithelium

skin of arm

mucosa of ileum

cerebellar vermis

external globus pallidus

gingival epithelium

right frontal lobe

Top expressed in

spermatocyte

epiblast

otolith organ

hand

utricle

cumulus cell

superior cervical ganglion

tail of embryo

primary oocyte

seminiferous tubule

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	histone binding zinc ion binding protein binding metal ion binding methylated histone binding
Cellular component	nucleus nucleoplasm
Biological process	regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of G0 to G1 transition chromatin organization
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


83746


214669

Ensembl


ENSG00000100395


ENSMUSG00000022394

UniProt


Q969R5


P59178

RefSeq (mRNA)


NM_001003689 NM_031488


NM_001289711 NM_001289712 NM_145993

RefSeq (protein)


NP_113676


NP_001276640 NP_001276641 NP_666105

Location (UCSC)

Chr 22: 41.21 – 41.23 Mb

Chr 15: 81.55 – 81.57 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Lethal(3)malignant brain tumor-like 2 protein is a protein that in humans is encoded by the L3MBTL2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100395 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022394 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wismar J (Oct 2001). "Molecular characterization of h-l(3)mbt-like: a new member of the human mbt family". FEBS Letters. 507 (1): 119–21. doi:10.1016/S0014-5793(01)02959-3. PMID 11682070.
^ "Entrez Gene: L3MBTL2 l(3)mbt-like 2 (Drosophila)".

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