LRRC17

Protein-coding gene in the species Homo sapiens
LRRC17
Identifiers
AliasesLRRC17, P37NB, leucine rich repeat containing 17
External IDsMGI: 1921761; HomoloGene: 55929; GeneCards: LRRC17; OMA:LRRC17 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for LRRC17
Genomic location for LRRC17
Band7q22.1Start102,913,000 bp[1]
End102,945,111 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for LRRC17
Genomic location for LRRC17
Band5|5 A3Start21,748,557 bp[2]
End21,780,902 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • periodontal fiber

  • right coronary artery

  • left ovary

  • right ovary

  • ventricular zone

  • Descending thoracic aorta

  • gallbladder

  • vena cava

  • left coronary artery
Top expressed in
  • dermis

  • secondary oocyte

  • efferent ductule

  • zygote

  • belly cord

  • ovarian follicle

  • secondary follicle of ovary

  • hand

  • primary oocyte

  • calvaria
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

10234

74511

Ensembl

ENSG00000128606

ENSMUSG00000039883

UniProt

Q8N6Y2

Q9CXD9

RefSeq (mRNA)

NM_001031692
NM_005824

NM_028977

RefSeq (protein)

NP_001026862
NP_005815

NP_083253

Location (UCSC)Chr 7: 102.91 – 102.95 MbChr 5: 21.75 – 21.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Leucine-rich repeat-containing protein 17 is a protein that in humans is encoded by the LRRC17 gene.[5][6][7]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128606 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039883 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kim D, LaQuaglia MP, Yang SY (Jan 1997). "A cDNA encoding a putative 37 kDa leucine-rich repeat (LRR) protein, p37NB, isolated from S-type neuroblastoma cell has a differential tissue distribution". Biochim Biophys Acta. 1309 (3): 183–8. doi:10.1016/s0167-4781(96)00158-3. PMID 8982252.
  6. ^ Kim T, Kim K, Lee SH, So HS, Lee J, Kim N, Choi Y (May 2009). "Identification of LRRc17 as a Negative Regulator of Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation". J Biol Chem. 284 (22): 15308–16. doi:10.1074/jbc.M807722200. PMC 2685711. PMID 19336404.
  7. ^ "Entrez Gene: LRRC17 leucine rich repeat containing 17".

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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