METTL14 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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5IL1, 5K7W, 5IL2, 5IL0, 5K7M, 5K7U |
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Identifiers |
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Aliases | METTL14, methyltransferase like 14, hmethyltransferase 14, N6-adenosine-methyltransferase subunit |
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External IDs | OMIM: 616504; MGI: 2442926; HomoloGene: 10865; GeneCards: METTL14; OMA:METTL14 - orthologs |
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Gene location (Human) |
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![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
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| Band | 4q26 | Start | 118,685,392 bp[1] |
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End | 118,715,433 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 G1 | Start | 123,161,946 bp[2] |
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End | 123,179,757 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Achilles tendon
- secondary oocyte
- tail of epididymis
- islet of Langerhans
- caput epididymis
- corpus epididymis
- ventricular zone
- epithelium of colon
- thymus
- pancreatic epithelial cell
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| Top expressed in | - hand
- ascending aorta
- aortic valve
- otolith organ
- utricle
- primitive streak
- tail of embryo
- efferent ductule
- epiblast
- supraoptic nucleus
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - RNA binding
- mRNA binding
- S-adenosyl-L-methionine binding
- protein binding
- mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
| Cellular component | - RNA N6-methyladenosine methyltransferase complex
- nucleus
- nucleoplasm
| Biological process | - stem cell population maintenance
- mRNA splicing, via spliceosome
- mRNA destabilization
- mRNA methylation
- RNA methylation
- mRNA catabolic process
- spermatogenesis
- forebrain radial glial cell differentiation
- gliogenesis
- cell differentiation
- RNA metabolic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 4: 118.69 – 118.72 Mb | Chr 3: 123.16 – 123.18 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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