NEURL1 |
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Identifiers |
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Aliases | NEURL1, NEUR1, NEURL, RNF67, bA416N2.1, neu, neu-1, neuralized E3 ubiquitin protein ligase 1 |
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External IDs | OMIM: 603804; MGI: 1334263; HomoloGene: 32503; GeneCards: NEURL1; OMA:NEURL1 - orthologs |
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Gene location (Human) |
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![Chromosome 10 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png) | Chr. | Chromosome 10 (human)[1] |
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| Band | 10q24.33 | Start | 103,493,705 bp[1] |
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End | 103,592,546 bp[1] |
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Gene location (Mouse) |
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![Chromosome 19 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/8/82/Ideogram_house_mouse_chromosome_19.svg/260px-Ideogram_house_mouse_chromosome_19.svg.png) | Chr. | Chromosome 19 (mouse)[2] |
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| Band | 19 C3|19 39.39 cM | Start | 47,167,259 bp[2] |
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End | 47,247,880 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - muscle of thigh
- right hemisphere of cerebellum
- gastrocnemius muscle
- right frontal lobe
- cingulate gyrus
- anterior cingulate cortex
- prefrontal cortex
- nucleus accumbens
- Brodmann area 9
- amygdala
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| Top expressed in | - muscle of thigh
- superior frontal gyrus
- triceps brachii muscle
- primary visual cortex
- temporal muscle
- dentate gyrus of hippocampal formation granule cell
- sternocleidomastoid muscle
- skeletal muscle tissue
- digastric muscle
- vastus lateralis muscle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_NEURL_204889_s_at_fs.png/250px-PBB_GE_NEURL_204889_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/3/38/PBB_GE_NEURL_204888_s_at_fs.png/250px-PBB_GE_NEURL_204888_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - translation factor activity, non-nucleic acid binding
- ubiquitin protein ligase activity
- metal ion binding
- ubiquitin-protein transferase activity
- transferase activity
| Cellular component | - cytoplasm
- perikaryon
- postsynaptic membrane
- cell projection
- membrane
- postsynaptic density
- plasma membrane
- dendritic spine
- synapse
- cell junction
- dendrite
- perinuclear region of cytoplasm
- apical dendrite
| Biological process | - Notch signaling pathway
- flagellated sperm motility
- positive regulation of epidermal growth factor-activated receptor activity
- positive regulation of dendritic spine development
- protein monoubiquitination
- nervous system development
- sperm axoneme assembly
- positive regulation of synapse maturation
- brain development
- positive regulation of long-term neuronal synaptic plasticity
- protein ubiquitination
- positive regulation of apoptotic process
- cellular response to amino acid stimulus
- lactation
- skeletal muscle tissue development
- positive regulation of filopodium assembly
- regulation of translation
- negative regulation of cell population proliferation
- negative regulation of Notch signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 10: 103.49 – 103.59 Mb | Chr 19: 47.17 – 47.25 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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