Protein-coding gene in the species Homo sapiens
NLRP13 |
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Identifiers |
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Aliases | NLRP13, CLR19.7, NALP13, NOD14, PAN13, NLR family, pyrin domain containing 13, NLR family pyrin domain containing 13 |
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External IDs | OMIM: 609660; HomoloGene: 65313; GeneCards: NLRP13; OMA:NLRP13 - orthologs |
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Gene location (Human) |
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![Chromosome 19 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/5/54/Ideogram_human_chromosome_19.svg/300px-Ideogram_human_chromosome_19.svg.png) | Chr. | Chromosome 19 (human)[1] |
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| Band | 19q13.43 | Start | 55,891,699 bp[1] |
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End | 55,932,336 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - oocyte
- secondary oocyte
- epithelium of colon
- bone marrow cells
- testicle
- tonsil
- skeletal muscle tissue
- urinary bladder
- liver
- breast
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| | More reference expression data |
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BioGPS | |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 19: 55.89 – 55.93 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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NLRP13, short for NOD-like receptor family pyrin domain containing 13, is an intracellular protein of mammals. It is also known as NALP13, NOD14, PAN13, and CLR19.7, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.[3] The function of NLRP13 is currently unknown.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000173572 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Tschopp J, Martinon F, Burns K (February 2003). "NALPs: a novel protein family involved in inflammation". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287. S2CID 31417018.
Further reading
- Enjuanes A, Benavente Y, Bosch F, et al. (2008). "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia". Cancer Res. 68 (24): 10178–86. doi:10.1158/0008-5472.CAN-08-2221. PMID 19074885.
- Inohara N, Nuñez G (2003). "NODs: intracellular proteins involved in inflammation and apoptosis". Nat. Rev. Immunol. 3 (5): 371–82. doi:10.1038/nri1086. PMID 12766759. S2CID 8088987.