OSBPL8 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/0/01/Protein_OSBPL8_PDB_1v88.png/250px-Protein_OSBPL8_PDB_1v88.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | OSBPL8, MST120, MSTP120, ORP8, OSBP10, oxysterol binding protein like 8 |
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External IDs | OMIM: 606736; MGI: 2443807; HomoloGene: 68813; GeneCards: OSBPL8; OMA:OSBPL8 - orthologs |
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Gene location (Human) |
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![Chromosome 12 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Ideogram_human_chromosome_12.svg/300px-Ideogram_human_chromosome_12.svg.png) | Chr. | Chromosome 12 (human)[1] |
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| Band | 12q21.2 | Start | 76,351,797 bp[1] |
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End | 76,559,809 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 D1 | Start | 111,000,613 bp[2] |
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End | 111,133,110 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - lower lobe of lung
- lactiferous duct
- trabecular bone
- endothelial cell
- nipple
- skin of hip
- Achilles tendon
- visceral pleura
- trigeminal ganglion
- superficial temporal artery
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| Top expressed in | - olfactory tubercle
- zygote
- nucleus accumbens
- secondary oocyte
- cumulus cell
- olfactory epithelium
- myocardium of ventricle
- retinal pigment epithelium
- interventricular septum
- aortic valve
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/1/10/PBB_GE_OSBPL8_212582_at_fs.png/250px-PBB_GE_OSBPL8_212582_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/b/bc/PBB_GE_OSBPL8_212585_at_fs.png/250px-PBB_GE_OSBPL8_212585_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - phosphatidylserine binding
- cholesterol binding
- phosphatidylinositol-4-phosphate binding
- lipid binding
- phospholipid transporter activity
- sterol transporter activity
- sterol binding
| Cellular component | - integral component of membrane
- nuclear membrane
- endoplasmic reticulum membrane
- membrane
- cortical endoplasmic reticulum
- endoplasmic reticulum
- nucleus
- cytosol
- intracellular membrane-bounded organelle
| Biological process | - activation of protein kinase B activity
- positive regulation of protein kinase B signaling
- lipid transport
- protein localization to nuclear pore
- phospholipid transport
- negative regulation of cell migration
- negative regulation of sequestering of triglyceride
- positive regulation of insulin receptor signaling pathway
- fat cell differentiation
- phosphatidylserine acyl-chain remodeling
- transport
- sterol transport
- positive regulation of glucose import
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001003712 NM_020841 NM_001319652 NM_001319653 NM_001319655 |
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RefSeq (protein) | |
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NP_001003712 NP_001306581 NP_001306582 NP_001306584 NP_065892 |
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Location (UCSC) | Chr 12: 76.35 – 76.56 Mb | Chr 10: 111 – 111.13 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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