Opalin

Protein-coding gene in the species Homo sapiens
OPALIN
Identifiers
AliasesOPALIN, HTMP10, TMEM10, TMP10, oligodendrocytic myelin paranodal and inner loop protein
External IDsOMIM: 617200; MGI: 2657025; HomoloGene: 13237; GeneCards: OPALIN; OMA:OPALIN - orthologs
Gene location (Mouse)
Chromosome 19 (mouse)
Chr.Chromosome 19 (mouse)[1]
Chromosome 19 (mouse)
Genomic location for OPALIN
Genomic location for OPALIN
Band19|19 C3Start41,050,149 bp[1]
End41,065,552 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • external globus pallidus

  • corpus callosum

  • putamen

  • amygdala

  • caudate nucleus

  • hippocampus proper

  • substantia nigra

  • Brodmann area 9

  • internal globus pallidus

  • nucleus accumbens
Top expressed in
  • lumbar subsegment of spinal cord

  • white matter

  • anterior horn of spinal cord

  • nerve

  • white matter of cerebellum

  • facial motor nucleus

  • nucleus of stria terminalis

  • fornix of the brain

  • lateral geniculate nucleus

  • globus pallidus
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

93377

226115

Ensembl

n/a

ENSMUSG00000050121

UniProt

Q96PE5

Q7M750

RefSeq (mRNA)
NM_001040102
NM_001040103
NM_001284320
NM_001284321
NM_001284322

NM_001284323
NM_001284324
NM_001284326
NM_001284327
NM_033207

NM_153520

RefSeq (protein)
NP_001035191
NP_001035192
NP_001271249
NP_001271250
NP_001271251

NP_001271252
NP_001271253
NP_001271255
NP_001271256
NP_149984

NP_705740

Location (UCSC)n/aChr 19: 41.05 – 41.07 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Opalin is a protein that is encoded in humans by the OPALIN gene.[4][5][6]

References

  1. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050121 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Nobile C, Hinzmann B, Scannapieco P, Siebert R, Zimbello R, Perez-Tur J, et al. (Jan 2002). "Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia". Gene. 282 (1–2): 87–94. doi:10.1016/S0378-1119(01)00846-0. PMID 11814680.
  5. ^ Aruga J, Yoshikawa F, Nozaki Y, Sakaki Y, Toyoda A, Furuichi T (Sep 2007). "An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin". Journal of Neurochemistry. 102 (5): 1533–47. doi:10.1111/j.1471-4159.2007.04583.x. PMID 17442045. S2CID 4231906.
  6. ^ "Entrez Gene: TMEM10 transmembrane protein 10".

Further reading

  • Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
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