PDAP1

Protein-coding gene in the species Homo sapiens
PDAP1
Identifiers
AliasesPDAP1, HASPP28, PAP, PAP1, PDGFA associated protein 1
External IDsOMIM: 607075; MGI: 2448536; HomoloGene: 8927; GeneCards: PDAP1; OMA:PDAP1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for PDAP1
Genomic location for PDAP1
Band7q22.1Start99,392,048 bp[1]
End99,408,597 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for PDAP1
Genomic location for PDAP1
Band5|5 G2Start145,065,579 bp[2]
End145,077,048 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • gastric mucosa

  • tibial arteries

  • sural nerve

  • muscle layer of sigmoid colon

  • thoracic aorta

  • ascending aorta

  • left coronary artery

  • muscle of thigh

  • right coronary artery
Top expressed in
  • Rostral migratory stream

  • tail of embryo

  • primitive streak

  • mandibular prominence

  • maxillary prominence

  • genital tubercle

  • somite

  • abdominal wall

  • lacrimal gland

  • epiblast
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • RNA binding
Cellular component
  • extracellular region
  • ficolin-1-rich granule lumen
  • cytosol
  • plasma membrane
Biological process
  • signal transduction
  • cell population proliferation
  • neutrophil degranulation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

11333

231887

Ensembl

ENSG00000106244

ENSMUSG00000029623

UniProt

Q13442

Q3UHX2

RefSeq (mRNA)

NM_014891

NM_001033313

RefSeq (protein)

NP_055706

NP_001028485

Location (UCSC)Chr 7: 99.39 – 99.41 MbChr 5: 145.07 – 145.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

28 kDa heat- and acid-stable phosphoprotein is a protein that in humans is encoded by the PDAP1 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106244 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029623 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fischer WH, Schubert D (Jan 1997). "Characterization of a novel platelet-derived growth factor-associated protein". J Neurochem. 66 (5): 2213–6. doi:10.1046/j.1471-4159.1996.66052213.x. PMID 8780057. S2CID 28782367.
  6. ^ "Entrez Gene: PDAP1 PDGFA associated protein 1".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
  • LaRochelle WJ, Jeffers M, McDonald WF, et al. (2001). "PDGF-D, a new protease-activated growth factor". Nat. Cell Biol. 3 (5): 517–21. doi:10.1038/35074593. PMID 11331882. S2CID 19633551.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.


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