PHLDB2 |
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Identifiers |
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Aliases | PHLDB2, LL5b, LL5beta, pleckstrin homology like domain family B member 2 |
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External IDs | OMIM: 610298; MGI: 2444981; HomoloGene: 17100; GeneCards: PHLDB2; OMA:PHLDB2 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3q13.2 | Start | 111,732,497 bp[1] |
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End | 111,976,517 bp[1] |
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Gene location (Mouse) |
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![Chromosome 16 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/Ideogram_house_mouse_chromosome_16.svg/260px-Ideogram_house_mouse_chromosome_16.svg.png) | Chr. | Chromosome 16 (mouse)[2] |
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| Band | 16|16 B5 | Start | 45,566,606 bp[2] |
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End | 45,773,961 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - myocardium of left ventricle
- tail of epididymis
- parietal pleura
- placenta
- Achilles tendon
- decidua
- right ventricle
- cardiac muscle tissue of right atrium
- tibial arteries
- visceral pleura
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| Top expressed in | - genital tubercle
- renal corpuscle
- left lung lobe
- urothelium
- gastrula
- medullary collecting duct
- tunica media of zone of aorta
- transitional epithelium of urinary bladder
- calvaria
- Gonadal ridge
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein binding
- cadherin binding
| Cellular component | - plasma membrane
- intermediate filament cytoskeleton
- basal cortex
- cell leading edge
- membrane
- focal adhesion
- cytoplasm
- cytosol
| Biological process | - negative regulation of wound healing, spreading of epidermal cells
- regulation of epithelial to mesenchymal transition
- regulation of microtubule cytoskeleton organization
- positive regulation of basement membrane assembly involved in embryonic body morphogenesis
- negative regulation of stress fiber assembly
- regulation of gastrulation
- microtubule cytoskeleton organization
- negative regulation of focal adhesion assembly
- establishment of protein localization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_145753 NM_001134437 NM_001134438 NM_001134439 |
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NM_001252442 NM_153412 NM_001357078 |
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RefSeq (protein) | |
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NP_001127909 NP_001127910 NP_001127911 NP_665696 |
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NP_001239371 NP_700461 NP_001344007 |
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Location (UCSC) | Chr 3: 111.73 – 111.98 Mb | Chr 16: 45.57 – 45.77 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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