PITPNB

Protein-coding gene in the species Homo sapiens

PITPNB

Identifiers

Aliases

PITPNB, PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta

External IDs

OMIM: 606876; MGI: 1927542; HomoloGene: 4533; GeneCards: PITPNB; OMA:PITPNB - orthologs

Gene location (Human)

Chr.	Chromosome 22 (human)^[1]

Band	22q12.1	Start	27,851,669 bp^[1]
Band	22q12.1	End	27,920,134 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)^[2]

Band	5\|5 F	Start	111,478,629 bp^[2]
Band	5\|5 F	End	111,536,225 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

gingival epithelium

secondary oocyte

endothelial cell

middle temporal gyrus

germinal epithelium

Brodmann area 23

superficial temporal artery

hair follicle

cartilage tissue

parietal pleura

Top expressed in

condyle

fossa

ciliary body

hair follicle

retinal pigment epithelium

endothelial cell of lymphatic vessel

vestibular membrane of cochlear duct

conjunctival fornix

internal carotid artery

iris

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	lipid binding phosphatidylcholine transporter activity phosphatidylinositol transfer activity phosphatidylcholine binding phosphatidylinositol binding phospholipid transporter activity
Cellular component	cytoplasm Golgi membrane Golgi apparatus endoplasmic reticulum membrane intracellular anatomical structure
Biological process	lipid metabolism retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum nucleus organization phospholipid transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


23760


56305

Ensembl


ENSG00000180957


ENSMUSG00000050017

UniProt


P48739


P53811

RefSeq (mRNA)


NM_001284277 NM_001284278 NM_012399

NM_001301643 NM_001301644 NM_001301666 NM_019640 NM_001359215
NM_001359216 NM_001359217

RefSeq (protein)


NP_001271206 NP_001271207 NP_036531

NP_001288572 NP_001288573 NP_001288595 NP_062614 NP_001346144
NP_001346145 NP_001346146

Location (UCSC)

Chr 22: 27.85 – 27.92 Mb

Chr 5: 111.48 – 111.54 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.^[5]^[6]

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180957 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050017 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
^ ^a ^b "Entrez Gene: PITPNB phosphatidylinositol transfer protein, beta".