PLEKHB2 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Protein_PLEKHB2_PDB_2dhi.png/250px-Protein_PLEKHB2_PDB_2dhi.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3AJ4, 3VIA |
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Identifiers |
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Aliases | PLEKHB2, EVT2, pleckstrin homology domain containing B2 |
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External IDs | OMIM: 618452; MGI: 2385825; HomoloGene: 9938; GeneCards: PLEKHB2; OMA:PLEKHB2 - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2q21.1 | Start | 131,104,847 bp[1] |
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End | 131,353,709 bp[1] |
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Gene location (Mouse) |
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![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 B | Start | 34,889,057 bp[2] |
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End | 34,918,661 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - pons
- endothelial cell
- superior vestibular nucleus
- inferior ganglion of vagus nerve
- Pars compacta
- Brodmann area 23
- cerebellar vermis
- spinal ganglia
- lateral nuclear group of thalamus
- pars reticulata
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| Top expressed in | - choroid plexus of fourth ventricle
- medulla oblongata
- superior colliculus
- medial vestibular nucleus
- entorhinal cortex
- perirhinal cortex
- neural layer of retina
- pyloric antrum
- dorsal tegmental nucleus
- right kidney
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/PBB_GE_PLEKHB2_201411_s_at_fs.png/250px-PBB_GE_PLEKHB2_201411_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/PBB_GE_PLEKHB2_201410_at_fs.png/250px-PBB_GE_PLEKHB2_201410_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- phosphatidylinositol-3,4,5-trisphosphate binding
| Cellular component | - membrane
- recycling endosome membrane
- endosome
- integral component of membrane
| Biological process | - regulation of cell differentiation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001031706 NM_001100623 NM_001267062 NM_001267063 NM_001267064
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NM_001267065 NM_001267066 NM_001267067 NM_001267068 NM_001309448 NM_001309450 NM_001309451 NM_001309452 NM_017958 |
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NM_145516 NM_175421 NM_001357425 |
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RefSeq (protein) | NP_001094093 NP_001253991 NP_001253992 NP_001253993 NP_001253994
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NP_001253995 NP_001253996 NP_001253997 NP_001296377 NP_001296379 NP_001296380 NP_001296381 NP_060428 NP_001094093.1 |
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NP_663491 NP_780630 NP_001344354 |
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Location (UCSC) | Chr 2: 131.1 – 131.35 Mb | Chr 1: 34.89 – 34.92 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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