PLXND1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | PLXND1, PLEXD1, plexin D1 |
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External IDs | OMIM: 604282; MGI: 2154244; HomoloGene: 22866; GeneCards: PLXND1; OMA:PLXND1 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3q22.1 | Start | 129,555,214 bp[1] |
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End | 129,606,676 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 E3 | Start | 115,931,772 bp[2] |
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End | 115,971,966 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - upper lobe of left lung
- right coronary artery
- right lung
- tibial nerve
- canal of the cervix
- apex of heart
- body of uterus
- left uterine tube
- gallbladder
- left coronary artery
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| Top expressed in | - thymus
- external carotid artery
- ankle joint
- molar
- lumbar spinal ganglion
- internal carotid artery
- yolk sac
- atrium
- genital tubercle
- decidua
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d7/PBB_GE_PLXND1_38671_at_fs.png/250px-PBB_GE_PLXND1_38671_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/a/af/PBB_GE_PLXND1_212235_at_fs.png/250px-PBB_GE_PLXND1_212235_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein domain specific binding
- protein binding
- semaphorin receptor activity
| Cellular component | - integral component of membrane
- membrane
- plasma membrane
- lamellipodium
- integral component of plasma membrane
- lamellipodium membrane
- cell projection
- semaphorin receptor complex
| Biological process | - cardiac septum development
- outflow tract morphogenesis
- regulation of angiogenesis
- coronary vasculature development
- multicellular organism development
- aorta development
- angiogenesis
- dichotomous subdivision of terminal units involved in salivary gland branching
- branching involved in blood vessel morphogenesis
- synapse assembly
- positive regulation of protein binding
- endothelial cell migration
- semaphorin-plexin signaling pathway
- signal transduction
- negative regulation of cell adhesion
- regulation of cell shape
- regulation of cell migration
- positive regulation of axonogenesis
- regulation of GTPase activity
- positive regulation of transcription of Notch receptor target
- semaphorin-plexin signaling pathway involved in axon guidance
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 129.56 – 129.61 Mb | Chr 6: 115.93 – 115.97 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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