PNISR

Protein-coding gene in the species Homo sapiens
PNISR
Identifiers
AliasesPNISR, C6orf111, HSPC306, SFRS18, SRrp130, bA98I9.2, PNN-interacting serine/arginine-rich protein, PNN interacting serine and arginine rich protein
External IDsOMIM: 616653; MGI: 1913875; HomoloGene: 32802; GeneCards: PNISR; OMA:PNISR - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for PNISR
Genomic location for PNISR
Band6q16.2Start99,397,629 bp[1]
End99,425,331 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for PNISR
Genomic location for PNISR
Band4|4 A3Start21,847,583 bp[2]
End21,876,475 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right hemisphere of cerebellum

  • sural nerve

  • right uterine tube

  • left ovary

  • anterior pituitary

  • left lobe of thyroid gland

  • right ovary

  • body of uterus

  • right lobe of thyroid gland

  • Achilles tendon
Top expressed in
  • hand

  • lobe of cerebellum

  • cerebellar vermis

  • neural layer of retina

  • genital tubercle

  • medullary collecting duct

  • superior colliculus

  • tail of embryo

  • superior cervical ganglion

  • Rostral migratory stream
More reference expression data
BioGPS


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

25957

66625

Ensembl

ENSG00000132424

ENSMUSG00000028248

UniProt

Q8TF01

A2AJT4

RefSeq (mRNA)
NM_015491
NM_032870
NM_001322405
NM_001322406
NM_001322408

NM_001322410
NM_001322412
NM_001322413
NM_001322414
NM_001322415
NM_001322416
NM_001322417
NM_001322418
NM_001322419

NM_025669
NM_001369189
NM_001369190
NM_001369191

RefSeq (protein)
NP_001309334
NP_001309335
NP_001309337
NP_001309339
NP_001309341

NP_001309342
NP_001309343
NP_001309344
NP_001309345
NP_001309346
NP_001309347
NP_001309348
NP_056306
NP_116259

NP_079945
NP_001356118
NP_001356119
NP_001356120

Location (UCSC)Chr 6: 99.4 – 99.43 MbChr 4: 21.85 – 21.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Splicing factor, arginine/serine-rich 18 is a protein that in humans is encoded by the SFRS18 gene.[5]

Interactions

SFRS18 has been shown to interact with Pinin.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132424 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028248 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: C6orf111 chromosome 6 open reading frame 111".
  6. ^ Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. 44 (11). United States: 4715–23. doi:10.1167/iovs.03-0240. ISSN 0146-0404. PMID 14578391.

Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Zimowska G, Shi J, Munguba G, et al. (2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. 44 (11): 4715–23. doi:10.1167/iovs.03-0240. PMID 14578391.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
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