Potassium-dependent sodium-calcium exchanger

Potassium-dependent sodium-calcium exchanger also known as solute carrier family 24 (SLC24) is a type of sodium-calcium exchanger that requires potassium to function.[1]

Family members

Human genes that encode members of the potassium-dependent sodium-calcium exchanger family include:

solute carrier family 24, member 1
Identifiers
SymbolSLC24A1
Alt. symbolsNCKX1
NCBI gene9187
HGNC10975
OMIM603617
RefSeqNM_004727
UniProtO60721
Other data
LocusChr. 15 q22
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solute carrier family 24, member 2
Identifiers
SymbolSLC24A2
Alt. symbolsNCKX2
NCBI gene25769
HGNC10976
OMIM609838
RefSeqNM_020344
UniProtQ9UI40
Other data
LocusChr. 9 p22-p13
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solute carrier family 24, member 3
Identifiers
SymbolSLC24A3
Alt. symbolsNCKX3
NCBI gene57419
HGNC10977
OMIM609839
RefSeqNM_020689
UniProtQ9HC58
Other data
LocusChr. 20 p13
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DomainsInterPro
solute carrier family 24, member 4
Identifiers
SymbolSLC24A4
Alt. symbolsNCKX4
NCBI gene123041
HGNC10978
OMIM609840
RefSeqNM_153646
UniProtQ8NFF2
Other data
LocusChr. 14 q32
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solute carrier family 24, member 5
Identifiers
SymbolSLC24A5
Alt. symbolsNCKX5
NCBI gene283652
HGNC20611
OMIM609802
RefSeqNM_205850
UniProtQ71RS6
Other data
LocusChr. 15 q15.2
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solute carrier family 24, member 6
Identifiers
SymbolSLC24A6
Alt. symbolsNCKX6
NCBI gene80024
HGNC26175
OMIM609841
RefSeqNM_024959
UniProtQ6J4K2
Other data
LocusChr. 12 q24
Search for
StructuresSwiss-model
DomainsInterPro

References

  1. ^ Schnetkamp PP (February 2004). "The SLC24 Na+/Ca2+-K+ exchanger family: vision and beyond". Pflügers Archiv. 447 (5): 683–8. doi:10.1007/s00424-003-1069-0. PMID 14770312. S2CID 37553960.

External links

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F-, V-, and A-type ATPase (3.A.2)
H+ (F-type)
H+ (V-type)
A-ATPase
found in Archea
P-type ATPase (3.A.3)
  • 3.A.3.1.2: H+/K+
  • H+/K+ exchanging: ATP4A
  • ATP4B
  • 3.A.3.1.4: H+/K+ transporting, nongastric: ATP12A
  • Other/ungrouped:
  • Na+/K+ – H+
see also ATPase disorders
  • v
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By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
  • Na+/Ca2+ exchanger
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
  • Na+-dependent ascorbic acid transporter
(24):
  • Na+/(Ca2+-K+) exchanger
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
  • basolateral iron transporter
SLC41–48
(41):
(42):
(43):
  • Na+-independent, system-L like amino-acid transporter
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter, Cotransporter
  • Na+/K+,Cl−
  • Na+/Pi3
  • Na+/Cl−
  • Na+/glucose
  • Na+/I−
  • Cl−/K+
Antiporter (exchanger)
  • Na+/H+
  • Na+/Ca2+
    • Na+/(Ca2+-K+) - Cl−/HCO−
      3       (Band 3)
  • Cl−-formate
  • Cl−-oxalate
see also solute carrier disorders


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