RAB30

Protein-coding gene in the species Homo sapiens
RAB30
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2EW1

Identifiers
AliasesRAB30, member RAS oncogene family
External IDsOMIM: 605693; MGI: 1923235; HomoloGene: 22815; GeneCards: RAB30; OMA:RAB30 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for RAB30
Genomic location for RAB30
Band11q14.1Start82,973,133 bp[1]
End83,071,923 bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for RAB30
Genomic location for RAB30
Band7|7 E1Start92,390,811 bp[2]
End92,493,743 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • internal globus pallidus

  • corpus callosum

  • secondary oocyte

  • external globus pallidus

  • pars reticulata

  • Pars compacta

  • Brodmann area 23

  • inferior ganglion of vagus nerve

  • endothelial cell

  • superior vestibular nucleus
Top expressed in
  • epithelium of small intestine

  • yolk sac

  • trigeminal ganglion

  • lobe of cerebellum

  • cerebellar vermis

  • pontine nuclei

  • facial motor nucleus

  • lateral geniculate nucleus

  • medial vestibular nucleus

  • deep cerebellar nuclei
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • nucleotide binding
  • GTP binding
  • GTPase activity
Cellular component
  • cis-Golgi network
  • Golgi apparatus
  • trans-Golgi network
  • Golgi stack
  • membrane
  • Golgi cisterna
  • Golgi membrane
  • cytoplasm
  • intracellular membrane-bounded organelle
  • endoplasmic reticulum membrane
Biological process
  • Golgi organization
  • intracellular protein transport
  • endoplasmic reticulum to Golgi vesicle-mediated transport
  • Rab protein signal transduction
  • small GTPase mediated signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

27314

75985

Ensembl

ENSG00000137502

ENSMUSG00000030643

UniProt

Q15771

Q923S9

RefSeq (mRNA)

NM_014488
NM_001286059
NM_001286060
NM_001286061

NM_029494

RefSeq (protein)
NP_001272988
NP_001272989
NP_001272990
NP_055303
NP_001272988.1

NP_001272989.1
NP_001272990.1
NP_055303.2

NP_083770

Location (UCSC)Chr 11: 82.97 – 83.07 MbChr 7: 92.39 – 92.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RAB30, member RAS oncogene family is a protein that in humans is encoded by the RAB30 gene. [5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137502 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030643 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RAB30, member RAS oncogene family". Retrieved 2017-06-15.

Further reading

  • Kelly EE, Giordano F, Horgan CP, Jollivet F, Raposo G, McCaffrey MW (2012). "Rab30 is required for the morphological integrity of the Golgi apparatus". Biology of the Cell. 104 (2): 84–101. doi:10.1111/boc.201100080. PMID 22188167. S2CID 13429621.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Ras-related protein Rab-30


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