RASGRF1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | RASGRF1, CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1, Ras protein specific guanine nucleotide releasing factor 1 |
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External IDs | OMIM: 606600; MGI: 99694; HomoloGene: 74972; GeneCards: RASGRF1; OMA:RASGRF1 - orthologs |
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Gene location (Human) |
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![Chromosome 15 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/07/Ideogram_human_chromosome_15.svg/300px-Ideogram_human_chromosome_15.svg.png) | Chr. | Chromosome 15 (human)[1] |
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| Band | 15q25.1 | Start | 78,959,906 bp[1] |
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End | 79,090,780 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9 E3.1|9 47.31 cM | Start | 89,791,961 bp[2] |
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End | 89,909,030 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - C1 segment
- right hemisphere of cerebellum
- prefrontal cortex
- right frontal lobe
- Brodmann area 9
- cingulate gyrus
- anterior cingulate cortex
- postcentral gyrus
- islet of Langerhans
- superior frontal gyrus
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| Top expressed in | - pontine nuclei
- paraventricular nucleus of hypothalamus
- dorsal tegmental nucleus
- dorsomedial hypothalamic nucleus
- subiculum
- motor neuron
- arcuate nucleus
- suprachiasmatic nucleus
- lateral hypothalamus
- anterior amygdaloid area
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - guanyl-nucleotide exchange factor activity
- glutamate receptor binding
| Cellular component | - cytosol
- growth cone
- neuron projection
- plasma membrane
| Biological process | - intracellular signal transduction
- MAPK cascade
- regulation of Rho protein signal transduction
- positive regulation of GTPase activity
- signal transduction
- regulation of Rac protein signal transduction
- regulation of synaptic plasticity
- long-term memory
- regulation of Ras protein signal transduction
- regulation of neuronal synaptic plasticity
- neuron projection development
- regulation of NMDA receptor activity
- activation of GTPase activity
- cell population proliferation
- small GTPase mediated signal transduction
- positive regulation of Ras protein signal transduction
- response to endoplasmic reticulum stress
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001145648 NM_002891 NM_153815 |
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NM_001039655 NM_011245 NM_001357743 NM_001357744 |
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RefSeq (protein) | |
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NP_001139120 NP_002882 NP_722522 |
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NP_001034744 NP_035375 NP_001344672 NP_001344673 |
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Location (UCSC) | Chr 15: 78.96 – 79.09 Mb | Chr 9: 89.79 – 89.91 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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