RBP7

Protein-coding gene in the species Homo sapiens
RBP7
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1LPJ

Identifiers
AliasesRBP7, CRBP4, CRBPIV, retinol binding protein 7, CRABP4
External IDsOMIM: 608604; MGI: 1890409; HomoloGene: 32521; GeneCards: RBP7; OMA:RBP7 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for RBP7
Genomic location for RBP7
Band1p36.22Start9,997,206 bp[1]
End10,016,021 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for RBP7
Genomic location for RBP7
Band4|4 E2Start149,534,144 bp[2]
End149,539,435 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • abdominal fat

  • pericardium

  • subcutaneous adipose tissue

  • monocyte

  • spleen

  • apex of heart

  • granulocyte

  • vena cava

  • gastric mucosa

  • tendon of biceps brachii
Top expressed in
  • interventricular septum

  • soleus muscle

  • brown adipose tissue

  • white adipose tissue

  • myocardium of ventricle

  • muscle of thigh

  • right ventricle

  • subcutaneous adipose tissue

  • intercostal muscle

  • left ventricle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • retinol binding
  • protein binding
  • retinoid binding
  • retinal binding
  • lipid binding
Cellular component
  • cytoplasm
Biological process
  • transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

116362

63954

Ensembl

ENSG00000162444

ENSMUSG00000028996

UniProt

Q96R05

Q9EPC5

RefSeq (mRNA)

NM_052960

NM_022020

RefSeq (protein)

NP_443192

NP_071303

Location (UCSC)Chr 1: 10 – 10.02 MbChr 4: 149.53 – 149.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Retinol binding protein 7 is a protein that in humans is encoded by the RBP7 gene. [5]

Function

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016].

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162444 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028996 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Retinol binding protein 7". Retrieved 2018-01-11.
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Retinoid-binding protein 7


Further reading


  • v
  • t
  • e

This article incorporates text from the United States National Library of Medicine, which is in the public domain.