Protein-coding gene in humans
| RNF26 |
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| Identifiers |
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| Aliases | RNF26, ring finger protein 26 |
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| External IDs | OMIM: 606130; MGI: 2388131; HomoloGene: 12924; GeneCards: RNF26; OMA:RNF26 - orthologs |
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| Gene location (Human) |
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 | | Chr. | Chromosome 11 (human)[1] |
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| | Band | 11q23.3 | Start | 119,334,527 bp[1] |
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| End | 119,337,309 bp[1] |
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| Gene location (Mouse) |
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 | | Chr. | Chromosome 9 (mouse)[2] |
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| | Band | 9|9 A5.1 | Start | 44,006,928 bp[2] |
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| End | 44,024,814 bp[2] |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - mucosa of ileum
- ventricular zone
- stromal cell of endometrium
- mucosa of transverse colon
- smooth muscle tissue
- prefrontal cortex
- right coronary artery
- popliteal artery
- tibial arteries
- body of stomach
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| | Top expressed in | - tracheobronchial tree
- trachea
- choroid plexus
- choroid plexus of fourth ventricle
- embryonic cell
- zygote
- primary motor cortex
- medulla oblongata
- pons
- secondary oocyte
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| | More reference expression data |
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| BioGPS | |
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| Gene ontology |
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| Molecular function | - metal ion binding
- protein binding
- zinc ion binding
- ubiquitin protein ligase activity
- transferase activity
| | Cellular component | - integral component of membrane
- membrane
- endoplasmic reticulum
- endoplasmic reticulum membrane
| | Biological process | - endosome organization
- regulation of type I interferon production
- negative regulation of defense response to virus
- protein K11-linked ubiquitination
- protein localization to perinuclear region of cytoplasm
- protein ubiquitination
| | Sources:Amigo / QuickGO |
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| Orthologs |
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| Species | Human | Mouse |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Location (UCSC) | Chr 11: 119.33 – 119.34 Mb | Chr 9: 44.01 – 44.02 Mb |
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| PubMed search | [3] | [4] |
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| Wikidata |
| View/Edit Human | View/Edit Mouse |
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Ring finger protein 26 is a protein that in humans is encoded by the RNF26 gene. [5]
Function
The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000173456 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053128 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Ring finger protein 26". Retrieved 2013-07-15.
Further reading
- Katoh M (April 2001). "Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper". Biochemical and Biophysical Research Communications. 282 (4): 1038–44. doi:10.1006/bbrc.2001.4671. PMID 11352657.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
