RNF32

Protein-coding gene in the species Homo sapiens
RNF32
Identifiers
AliasesRNF32, FKSG33, HSD15, LMBR2, ring finger protein 32
External IDsOMIM: 610241; MGI: 1861747; HomoloGene: 10986; GeneCards: RNF32; OMA:RNF32 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for RNF32
Genomic location for RNF32
Band7q36.3Start156,640,281 bp[1]
End156,677,130 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for RNF32
Genomic location for RNF32
Band5 B1|5 14.78 cMStart29,400,990 bp[2]
End29,433,455 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • sperm

  • testicle

  • bronchial epithelial cell

  • C1 segment

  • right uterine tube

  • gonad

  • islet of Langerhans

  • left adrenal cortex
Top expressed in
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • interventricular septum

  • genital tubercle

  • zygote

  • secondary oocyte

  • primary oocyte

  • urethra

  • female urethra
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

140545

56874

Ensembl

ENSG00000105982

ENSMUSG00000029130

UniProt

Q9H0A6

Q9JIT1

RefSeq (mRNA)

NM_001184996
NM_001184997
NM_001308273
NM_001308274
NM_030936

NM_001289757
NM_021470

RefSeq (protein)

NP_001171925
NP_001171926
NP_001295202
NP_001295203
NP_112198

NP_001276686
NP_067445

Location (UCSC)Chr 7: 156.64 – 156.68 MbChr 5: 29.4 – 29.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RING finger protein 32 is a protein that in humans is encoded by the RNF32 gene.[5][6]

The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Several alternatively spliced transcript variants exist, but their full length natures are not clear.[6]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105982 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029130 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ van Baren MJ, van der Linde HC, Breedveld GJ, Baarends WM, Rizzu P, de Graaff E, Oostra BA, Heutink P (Mar 2002). "A double RING-H2 domain in RNF32, a gene expressed during sperm formation". Biochem Biophys Res Commun. 292 (1): 58–65. doi:10.1006/bbrc.2002.6612. PMID 11890671.
  6. ^ a b "Entrez Gene: RNF32 ring finger protein 32".

Further reading

  • Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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