SASH1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Protein_SASH1_PDB_2dl0.png/250px-Protein_SASH1_PDB_2dl0.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SASH1, SH3D6A, dJ323M4, dJ323M4.1, SAM and SH3 domain containing 1, DUH1, CAPOK |
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External IDs | OMIM: 607955; MGI: 1917347; HomoloGene: 69182; GeneCards: SASH1; OMA:SASH1 - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6q24.3-q25.1 | Start | 148,272,304 bp[1] |
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End | 148,552,044 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 A1 | Start | 8,597,983 bp[2] |
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End | 8,761,814 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - synovial joint
- external globus pallidus
- skin of hip
- subthalamic nucleus
- skin of thigh
- inferior ganglion of vagus nerve
- oral cavity
- pars reticulata
- Achilles tendon
- lateral nuclear group of thalamus
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| Top expressed in | - stroma of bone marrow
- transitional epithelium of urinary bladder
- medial geniculate nucleus
- lateral geniculate nucleus
- substantia nigra
- suprachiasmatic nucleus
- ventral tegmental area
- medial dorsal nucleus
- lateral hypothalamus
- deep cerebellar nuclei
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/b/b2/PBB_GE_SASH1_213236_at_fs.png/250px-PBB_GE_SASH1_213236_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/5/56/PBB_GE_SASH1_41644_at_fs.png/250px-PBB_GE_SASH1_41644_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - mitogen-activated protein kinase kinase kinase binding
- molecular adaptor activity
- protein C-terminus binding
- protein kinase binding
| Cellular component | - protein-containing complex
| Biological process | - positive regulation of endothelial cell migration
- positive regulation of lipopolysaccharide-mediated signaling pathway
- positive regulation of JUN kinase activity
- regulation of protein K63-linked ubiquitination
- positive regulation of p38MAPK cascade
- regulation of protein autoubiquitination
- protein polyubiquitination
- positive regulation of NIK/NF-kappaB signaling
- positive regulation of angiogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_015278 NM_001346505 NM_001346506 NM_001346507 NM_001346508
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NM_001346509 |
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RefSeq (protein) | NP_001333434 NP_001333435 NP_001333436 NP_001333437 NP_001333438
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NP_056093 |
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Location (UCSC) | Chr 6: 148.27 – 148.55 Mb | Chr 10: 8.6 – 8.76 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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