SCGB3A2

Protein-coding gene in the species Homo sapiens
SCGB3A2
Identifiers
AliasesSCGB3A2, LU103, PNSP1, UGRP1, pnSP-1, secretoglobin family 3A member 2
External IDsOMIM: 606531; MGI: 2153470; HomoloGene: 14274; GeneCards: SCGB3A2; OMA:SCGB3A2 - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for SCGB3A2
Genomic location for SCGB3A2
Band5q32Start147,870,682 bp[1]
End147,882,191 bp[1]
Gene location (Mouse)
Chromosome 18 (mouse)
Chr.Chromosome 18 (mouse)[2]
Chromosome 18 (mouse)
Genomic location for SCGB3A2
Genomic location for SCGB3A2
Band18|18 B3Start43,897,354 bp[2]
End43,900,464 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • trachea

  • right lung

  • lower lobe of lung

  • upper lobe of lung

  • upper lobe of left lung

  • oocyte

  • gonad

  • visceral pleura

  • testicle

  • secondary oocyte
Top expressed in
  • right lung lobe

  • tracheobronchial tree

  • trachea

  • left lung

  • left lung lobe

  • epithelium of bronchus

  • epithelium of bronchiole

  • external carotid artery

  • atrioventricular valve

  • main bronchus
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

117156

117158

Ensembl

ENSG00000164265

ENSMUSG00000038791

UniProt

Q96PL1

Q920H1

RefSeq (mRNA)

NM_054023

NM_001289643
NM_001289644
NM_054038

RefSeq (protein)

NP_473364

NP_001276572
NP_001276573

Location (UCSC)Chr 5: 147.87 – 147.88 MbChr 18: 43.9 – 43.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Secretoglobin family 3A member 2 is a protein that in humans is encoded by the SCGB3A2 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164265 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038791 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: SCGB3A2 secretoglobin, family 3A, member 2".

Further reading

  • Kimura S, Hara Y, Pineau T, et al. (1996). "The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary". Genes Dev. 10 (1): 60–9. doi:10.1101/gad.10.1.60. PMID 8557195.
  • Wattiez R, Hermans C, Cruyt C, et al. (2001). "Human bronchoalveolar lavage fluid protein two-dimensional database: study of interstitial lung diseases". Electrophoresis. 21 (13): 2703–12. doi:10.1002/1522-2683(20000701)21:13<2703::AID-ELPS2703>3.0.CO;2-W. PMID 10949149. S2CID 38601731.
  • Niimi T, Munakata M, Keck-Waggoner CL, et al. (2002). "A Polymorphism in the Human UGRP1 Gene Promoter That Regulates Transcription Is Associated with an Increased Risk of Asthma". Am. J. Hum. Genet. 70 (3): 718–25. doi:10.1086/339272. PMC 384948. PMID 11813133.
  • Porter D, Lahti-Domenici J, Torres-Arzayus M, et al. (2003). "Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues". Mech. Dev. 114 (1–2): 201–4. doi:10.1016/S0925-4773(02)00056-4. PMID 12175512. S2CID 1770009.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Bin LH, Nielson LD, Liu X, et al. (2003). "Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair". J. Immunol. 171 (2): 924–30. doi:10.4049/jimmunol.171.2.924. PMID 12847263.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Srisodsai A, Kurotani R, Chiba Y, et al. (2005). "Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1". J. Biol. Chem. 279 (52): 54358–68. doi:10.1074/jbc.M405331200. PMID 15485815.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.


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