SERINC1 |
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Identifiers |
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Aliases | SERINC1, TDE1L, TDE2, TMS-2, TMS2, serine incorporator 1 |
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External IDs | OMIM: 614548; MGI: 1926228; HomoloGene: 41334; GeneCards: SERINC1; OMA:SERINC1 - orthologs |
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Gene location (Human) |
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![Chromosome 6 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | Chr. | Chromosome 6 (human)[1] |
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| Band | 6q22.31 | Start | 122,443,351 bp[1] |
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End | 122,471,807 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 B4 | Start | 57,391,870 bp[2] |
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End | 57,408,626 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - pons
- lateral nuclear group of thalamus
- orbitofrontal cortex
- postcentral gyrus
- Pars compacta
- subthalamic nucleus
- pars reticulata
- superior vestibular nucleus
- external globus pallidus
- C1 segment
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| Top expressed in | - lobe of cerebellum
- cerebellar vermis
- ventral tegmental area
- medial dorsal nucleus
- dorsomedial hypothalamic nucleus
- dorsal tegmental nucleus
- medial geniculate nucleus
- subiculum
- paraventricular nucleus of hypothalamus
- mammillary body
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/0a/PBB_GE_SERINC1_208671_at_fs.png/250px-PBB_GE_SERINC1_208671_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- enzyme binding
- protein-macromolecule adaptor activity
- L-serine transmembrane transporter activity
| Cellular component | - plasma membrane
- endoplasmic reticulum membrane
- endoplasmic reticulum
- membrane
- integral component of membrane
| Biological process | - phosphatidylserine metabolic process
- positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
- positive regulation of serine C-palmitoyltransferase activity
- sphingolipid metabolic process
- phospholipid biosynthetic process
- lipid metabolism
- L-serine transport
- membrane biogenesis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 122.44 – 122.47 Mb | Chr 10: 57.39 – 57.41 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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