STAP1 |
---|
|
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
1X1F, 3MAZ |
|
|
Identifiers |
---|
Aliases | STAP1, BRDG1, STAP-1, signal transducing adaptor family member 1 |
---|
External IDs | OMIM: 604298; MGI: 1926193; HomoloGene: 8103; GeneCards: STAP1; OMA:STAP1 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
---|
| Band | 4q13.2 | Start | 67,558,727 bp[1] |
---|
End | 67,607,337 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 5 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_5.svg/260px-Ideogram_house_mouse_chromosome_5.svg.png) | Chr. | Chromosome 5 (mouse)[2] |
---|
| Band | 5|5 E1 | Start | 86,219,605 bp[2] |
---|
End | 86,253,984 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - lymph node
- epithelium of nasopharynx
- spleen
- appendix
- granulocyte
- bone marrow cells
- testicle
- tonsil
- superficial temporal artery
- blood
|
| Top expressed in | - granulocyte
- thymus
- spleen
- mesenteric lymph nodes
- olfactory epithelium
- blood
- lumbar spinal ganglion
- subcutaneous adipose tissue
- tibiofemoral joint
- lumbar subsegment of spinal cord
|
| More reference expression data |
|
---|
BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PBB_GE_BRDG1_220059_at_fs.png/250px-PBB_GE_BRDG1_220059_at_fs.png) | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - macrophage colony-stimulating factor receptor binding
- transmembrane receptor protein tyrosine kinase adaptor activity
- phosphotyrosine residue binding
- receptor tyrosine kinase binding
- protein binding
- phospholipid binding
- protein kinase binding
- signaling adaptor activity
| Cellular component | - cytoplasm
- mitochondrion
- nucleus
- nucleoplasm
- intracellular membrane-bounded organelle
- protein-containing complex
| Biological process | - positive regulation of B cell receptor signaling pathway
- positive regulation of phagocytosis, engulfment
- transmembrane receptor protein tyrosine kinase signaling pathway
- negative regulation of ruffle assembly
- positive regulation of microglial cell mediated cytotoxicity
- positive regulation of non-membrane spanning protein tyrosine kinase activity
- negative regulation of microglial cell migration
- positive regulation of gene expression
- positive regulation of microglial cell activation
- negative regulation of phosphorylation
- cellular response to lipopolysaccharide
- negative regulation of macrophage colony-stimulating factor signaling pathway
- positive regulation of actin cytoskeleton reorganization
- negative regulation of macrophage chemotaxis
- response to bacterium
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 4: 67.56 – 67.61 Mb | Chr 5: 86.22 – 86.25 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|