STRBP

Protein-coding gene in Homo sapiens
STRBP
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2DMY

Identifiers
AliasesSTRBP, HEL162, ILF3L, SPNR, p74, spermatid perinuclear RNA binding protein
External IDsOMIM: 611138; MGI: 104626; HomoloGene: 7548; GeneCards: STRBP; OMA:STRBP - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for STRBP
Genomic location for STRBP
Band9q33.3Start123,109,500 bp[1]
End123,268,586 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for STRBP
Genomic location for STRBP
Band2|2 BStart37,373,240 bp[2]
End37,593,871 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • primary visual cortex

  • lateral nuclear group of thalamus

  • Brodmann area 23

  • sperm

  • ganglionic eminence

  • endothelial cell

  • parietal lobe

  • postcentral gyrus

  • epithelium of nasopharynx
Top expressed in
  • tail of embryo

  • lacrimal gland

  • genital tubercle

  • zygote

  • medial dorsal nucleus

  • olfactory epithelium

  • Rostral migratory stream

  • medial geniculate nucleus

  • spermatocyte

  • secondary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • double-stranded RNA binding
  • protein binding
  • single-stranded RNA binding
  • RNA binding
  • microtubule binding
  • tubulin binding
Cellular component
  • cytoplasm
  • microtubule cytoskeleton
  • nucleus
  • manchette
Biological process
  • multicellular organism development
  • mechanosensory behavior
  • cell differentiation
  • spermatogenesis
  • spermatid development
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55342

20744

Ensembl

ENSG00000165209

ENSMUSG00000026915

UniProt

Q96SI9

Q91WM1

RefSeq (mRNA)

NM_001171137
NM_018387
NM_001376106
NM_001376107
NM_001376109

NM_009261
NM_176932
NM_001355259
NM_001379314
NM_001379315

NM_001379316

RefSeq (protein)

NP_001164608
NP_060857
NP_001363035
NP_001363036
NP_001363038

NP_033287
NP_001342188
NP_001366243
NP_001366244
NP_001366245

Location (UCSC)Chr 9: 123.11 – 123.27 MbChr 2: 37.37 – 37.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Spermatid perinuclear RNA-binding protein is a protein that in humans is encoded by the STRBP gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165209 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026915 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".

Further reading

  • Schumacher JM, Lee K, Edelhoff S, Braun RE (May 1995). "Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules". The Journal of Cell Biology. 129 (4): 1023–32. doi:10.1083/jcb.129.4.1023. PMC 2120489. PMID 7744952.
  • Schumacher JM, Artzt K, Braun RE (July 1998). "Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice". Biology of Reproduction. 59 (1): 69–76. doi:10.1095/biolreprod59.1.69. PMID 9674995.
  • Coolidge CJ, Patton JG (March 2000). "A new double-stranded RNA-binding protein that interacts with PKR". Nucleic Acids Research. 28 (6): 1407–17. doi:10.1093/nar/28.6.1407. PMC 111047. PMID 10684936.
  • Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P (May 2001). "Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities" (PDF). Developmental Biology. 233 (2): 319–28. doi:10.1006/dbio.2001.0169. hdl:11858/00-001M-0000-0012-F717-7. PMID 11336498.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • v
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  • e
  • 2dmy: Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein
    2dmy: Solution structure of DSRM domain in Spermatid perinuclear RNA-bind protein


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