TCF19

Protein-coding gene in the species Homo sapiens
TCF19
Identifiers
AliasesTCF19, SC1, TCF-19, transcription factor 19
External IDsOMIM: 600912; MGI: 103180; HomoloGene: 5156; GeneCards: TCF19; OMA:TCF19 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for TCF19
Genomic location for TCF19
Band6p21.33Start31,158,547 bp[1]
End31,167,159 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for TCF19
Genomic location for TCF19
Band17|17 B1Start35,823,631 bp[2]
End35,827,721 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • ventricular zone

  • lymph node

  • ganglionic eminence

  • mucosa of transverse colon

  • bone marrow

  • appendix

  • stromal cell of endometrium

  • mucosa of esophagus

  • bone marrow cells
Top expressed in
  • bone marrow

  • thymus

  • ventricular zone

  • genital tubercle

  • stomach

  • yolk sac

  • lip

  • intestine

  • duodenum

  • neural tube
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • metal ion binding
  • protein binding
Cellular component
  • nucleus
Biological process
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
  • cell population proliferation
  • regulation of transcription, DNA-templated
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

6941

106795

Ensembl
ENSG00000233890
ENSG00000224472
ENSG00000137310
ENSG00000224941
ENSG00000234674

ENSG00000206455
ENSG00000224379

ENSMUSG00000050410

UniProt

Q9Y242

Q99KJ5

RefSeq (mRNA)

NM_001077511
NM_007109
NM_001318908

NM_001163763
NM_001163764
NM_025674

RefSeq (protein)

NP_001070979
NP_001305837
NP_009040

NP_001157235
NP_001157236
NP_079950

Location (UCSC)Chr 6: 31.16 – 31.17 MbChr 17: 35.82 – 35.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription factor 19 is a protein that in humans is encoded by the TCF19 gene.[5][6][7]


References

  1. ^ a b c ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 GRCh38: Ensembl release 89: ENSG00000233890, ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050410 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ku DH, Chang CD, Koniecki J, Cannizzaro LA, Boghosian-Sell L, Alder H, Baserga R (Sep 1991). "A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor". Cell Growth Differ. 2 (4): 179–86. PMID 1868030.
  6. ^ Krishnan BR, Jamry I, Chaplin DD (Apr 1996). "Feature mapping of the HLA class I region: localization of the POU5F1 and TCF19 genes". Genomics. 30 (1): 53–8. doi:10.1006/geno.1995.0008. PMID 8595903.
  7. ^ "Entrez Gene: TCF19 transcription factor 19 (SC1)".

Further reading

  • Teraoka Y, Naruse TK, Oka A, et al. (2000). "Genetic polymorphisms in the cell growth regulated gene, SC1 telomeric of the HLA-C gene and lack of association of psoriasis vulgaris". Tissue Antigens. 55 (3): 206–11. doi:10.1034/j.1399-0039.2000.550303.x. PMID 10777095.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Shiina T, Ota M, Shimizu S, et al. (2006). "Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity". Genetics. 173 (3): 1555–70. doi:10.1534/genetics.106.057034. PMC 1526686. PMID 16702430.


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