THYN1
Protein-coding gene in the species Homo sapiens
THYN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | THYN1, MDS012, MY105, THY28, THY28KD, HSPC144, thymocyte nuclear protein 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 613739; MGI: 1925112; HomoloGene: 8575; GeneCards: THYN1; OMA:THYN1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Thymocyte nuclear protein 1 is a protein that in humans is encoded by the THYN1 gene.[5][6][7]
This gene encodes a protein that is highly conserved among vertebrates and plant species and may be involved in the induction of apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000151500 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035443 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Jiang XZ, Toyota H, Yoshimoto T, Takada E, Asakura H, Mizuguchi J (Nov 2003). "Anti-IgM-induced down-regulation of nuclear Thy28 protein expression in Ramos B lymphoma cells". Apoptosis. 8 (5): 509–19. doi:10.1023/A:1025594409056. PMID 14601557. S2CID 2092518.
- ^ Miyaji H, Yoshimoto T, Asakura H, Komachi A, Kamiya S, Takasaki M, Mizuguchi J (Oct 2002). "Molecular cloning and characterization of the mouse thymocyte protein gene". Gene. 297 (1–2): 189–96. doi:10.1016/S0378-1119(02)00886-7. PMID 12384300.
- ^ a b "Entrez Gene: THYN1 thymocyte nuclear protein 1".
Further reading
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
- Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Jiang X, Toyota H, Takada E, et al. (2004). "Modulation of mThy28 nuclear protein expression during thymocyte development". Tissue & Cell. 35 (6): 471–8. doi:10.1016/S0040-8166(03)00073-9. PMID 14580360.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Song AX, Chang YG, Gao YG, et al. (2005). "Identification, expression, and purification of a unique stable domain from human HSPC144 protein". Protein Expr. Purif. 42 (1): 146–52. doi:10.1016/j.pep.2005.03.008. PMID 15939300.
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